STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ta0835DNA helicase related protein; DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks. (674 aa)    
Predicted Functional Partners:
Ta0446
Translation elongation factor aEF-2 related protein; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translati [...]
  
 0.999
Ta0836
Similarity to unknown protein: hypothetical protein PAB0505 - Pyrococcus abyssi (strain Orsay); PIR:D75117.
 
     0.948
Ta0927
Weak similarity to known protein.
  
 0.867
Ta1240
Similarity to known protein: SMALL NUCLEAR RIBONUCLEOPROTEIN F (SNRNP-F) (SM PROTEIN F) (MEMBRANE-ASSOCIATED PROTEIN DEB-B) - Drosophila melanogaster (Fruit fly); SWISSPROT:RUXF_DROME; Belongs to the snRNP Sm proteins family.
  
 0.867
Ta1116
Probable 50S ribosomal protein L7; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
 
 0.828
Ta0297
Strong similarity to known protein: DEAD box protein - Klebsiella pneumoniae; PIR2:JX0314.
   
 0.784
Ta0949
Fibrillarin-like pre-rRNA processing protein related protein; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family.
   
 0.784
Ta1189
Probable glycine C-acetyltransferase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
   
    0.650
Ta0831
Strong similarity to unknown protein: hypothetical protein APE1964 - Aeropyrum pernix (strain K1); PIR:F72498. Relation: weak similarity to non-specific lipid transfer protein - rat, TREMBL:RNNSLIPTR_2.
       0.600
Ta0799
DNA replication licensing factor MCM related protein; Similarity to known protein: CDC21 PROTEIN.CDC21 PROTEIN - Schizosaccharomyces pombe (Fission yeast).Schizosaccharomyces pombe (Fission yeast); SWISSPROT:CC21_SCHPO; Belongs to the MCM family.
 
   
 0.586
Your Current Organism:
Thermoplasma acidophilum
NCBI taxonomy Id: 273075
Other names: T. acidophilum DSM 1728, Thermoplasma acidophilum DSM 1728
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.