Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Ta0255 | Ta0446 | gene:9571472 | gene:9571666 | Hypothetical protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. | Translation elongation factor aEF-2 related protein; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translati [...] | 0.993 |
| Ta0255 | Ta0525 | gene:9571472 | gene:9571743 | Hypothetical protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. | Strong similarity to unknown protein: hypothetical protein PH1257 - Pyrococcus horikoshii; PIR:E71070. | 0.580 |
| Ta0255 | Ta0883 | gene:9571472 | gene:9572097 | Hypothetical protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. | Methyltransferase DPH5 related protein (diphthamide biosynthesis); S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis. | 0.838 |
| Ta0255 | Ta1311 | gene:9571472 | gene:9572534 | Hypothetical protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. | Probable Histone and other Protein Acetyltransferase (yeast HPA1); Strong similarity to known protein: histone acetyltransferase (EC 2.3.1.48), RNA polymerase II-associated [validated] - yeast (Saccharomyces cerevisiae); PIR2:S61980. | 0.520 |
| Ta0446 | Ta0255 | gene:9571666 | gene:9571472 | Translation elongation factor aEF-2 related protein; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translati [...] | Hypothetical protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. | 0.993 |
| Ta0446 | Ta0525 | gene:9571666 | gene:9571743 | Translation elongation factor aEF-2 related protein; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translati [...] | Strong similarity to unknown protein: hypothetical protein PH1257 - Pyrococcus horikoshii; PIR:E71070. | 0.984 |
| Ta0446 | Ta0882 | gene:9571666 | gene:9572096 | Translation elongation factor aEF-2 related protein; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translati [...] | Enolase related protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.964 |
| Ta0446 | Ta0883 | gene:9571666 | gene:9572097 | Translation elongation factor aEF-2 related protein; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translati [...] | Methyltransferase DPH5 related protein (diphthamide biosynthesis); S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis. | 0.993 |
| Ta0446 | Ta1243 | gene:9571666 | gene:9572466 | Translation elongation factor aEF-2 related protein; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translati [...] | Similarity to known protein: NUCLEOLAR PROTEIN NOP56 - Homo sapiens (Human); SWISSPROT:NO56_HUMANFunction: probably involved in RNA splicing. | 0.469 |
| Ta0446 | Ta1259 | gene:9571666 | gene:9572482 | Translation elongation factor aEF-2 related protein; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translati [...] | Known protein: ribosomal protein s4e - Thermoplasma acidophilum; PIR:T37467; Belongs to the eukaryotic ribosomal protein eS4 family. | 0.999 |
| Ta0525 | Ta0255 | gene:9571743 | gene:9571472 | Strong similarity to unknown protein: hypothetical protein PH1257 - Pyrococcus horikoshii; PIR:E71070. | Hypothetical protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. | 0.580 |
| Ta0525 | Ta0446 | gene:9571743 | gene:9571666 | Strong similarity to unknown protein: hypothetical protein PH1257 - Pyrococcus horikoshii; PIR:E71070. | Translation elongation factor aEF-2 related protein; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translati [...] | 0.984 |
| Ta0525 | Ta0883 | gene:9571743 | gene:9572097 | Strong similarity to unknown protein: hypothetical protein PH1257 - Pyrococcus horikoshii; PIR:E71070. | Methyltransferase DPH5 related protein (diphthamide biosynthesis); S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis. | 0.879 |
| Ta0525 | Ta1259 | gene:9571743 | gene:9572482 | Strong similarity to unknown protein: hypothetical protein PH1257 - Pyrococcus horikoshii; PIR:E71070. | Known protein: ribosomal protein s4e - Thermoplasma acidophilum; PIR:T37467; Belongs to the eukaryotic ribosomal protein eS4 family. | 0.432 |
| Ta0836 | Ta0883 | gene:9572050 | gene:9572097 | Similarity to unknown protein: hypothetical protein PAB0505 - Pyrococcus abyssi (strain Orsay); PIR:D75117. | Methyltransferase DPH5 related protein (diphthamide biosynthesis); S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis. | 0.667 |
| Ta0836 | Ta1243 | gene:9572050 | gene:9572466 | Similarity to unknown protein: hypothetical protein PAB0505 - Pyrococcus abyssi (strain Orsay); PIR:D75117. | Similarity to known protein: NUCLEOLAR PROTEIN NOP56 - Homo sapiens (Human); SWISSPROT:NO56_HUMANFunction: probably involved in RNA splicing. | 0.567 |
| Ta0836 | Ta1259 | gene:9572050 | gene:9572482 | Similarity to unknown protein: hypothetical protein PAB0505 - Pyrococcus abyssi (strain Orsay); PIR:D75117. | Known protein: ribosomal protein s4e - Thermoplasma acidophilum; PIR:T37467; Belongs to the eukaryotic ribosomal protein eS4 family. | 0.422 |
| Ta0836 | Ta1311 | gene:9572050 | gene:9572534 | Similarity to unknown protein: hypothetical protein PAB0505 - Pyrococcus abyssi (strain Orsay); PIR:D75117. | Probable Histone and other Protein Acetyltransferase (yeast HPA1); Strong similarity to known protein: histone acetyltransferase (EC 2.3.1.48), RNA polymerase II-associated [validated] - yeast (Saccharomyces cerevisiae); PIR2:S61980. | 0.536 |
| Ta0880 | Ta0881 | gene:9572094 | gene:9572095 | Ribokinase related protein; Nucleoside kinase with broad substrate specificity. Catalyzes the phosphorylation of a variety of nucleosides to the corresponding nucleoside 5'-mono-phosphate in the presence of phosphate donors and divalent cations. Displays the most efficient activity with guanosine, followed by inosine, cytidine, and adenosine. Negligible enzymatic activity is detected with thymidine, uridine, and 2-deoxyadenosine. ATP is the most efficient phosphate donor, but can also use GTP and ITP. Shows no sugar kinase activity, since it is unable to phosphorylate ribose, fructose- [...] | Similarity to known protein: carbonate dehydratase (EC 4.2.1.1) precursor - Methanosarcina thermophila; PIR:A57712. | 0.801 |
| Ta0880 | Ta0882 | gene:9572094 | gene:9572096 | Ribokinase related protein; Nucleoside kinase with broad substrate specificity. Catalyzes the phosphorylation of a variety of nucleosides to the corresponding nucleoside 5'-mono-phosphate in the presence of phosphate donors and divalent cations. Displays the most efficient activity with guanosine, followed by inosine, cytidine, and adenosine. Negligible enzymatic activity is detected with thymidine, uridine, and 2-deoxyadenosine. ATP is the most efficient phosphate donor, but can also use GTP and ITP. Shows no sugar kinase activity, since it is unable to phosphorylate ribose, fructose- [...] | Enolase related protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.853 |
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