STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ta0977Methionine synthase (cobalamin-independent) related protein; Catalyzes the transfer of a methyl group to L-homocysteine resulting in methionine formation. The physiological methyl donor is unknown (By similarity). (343 aa)    
Predicted Functional Partners:
Ta0978
Conserved hypothetical protein; Similarity to unknown protein: tetrahydropteroyltriglutamate methyltransferase PAB2361 - Pyrococcus abyssi (strain Orsay); PIR:B75138.
    
  0.993
Ta0469
Probable adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
 
 
 0.974
Ta0979
Similarity to known protein: 5, 10-METHYLENETETRAHYDROFOLATE REDUCTASE (EC 1.7.99.5) - Streptomyces lividans; SWISSPROT:METF_STRLI.
  
 
 0.972
Ta0080
Similarity to known protein: cystathionine gamma-lyase (EC 4.4.1.1) - rat; PIR:A49864Function: Methionine metabolism, Selenoamino acid metabolism, Nitrogen metabolism.
  
 
 0.964
Ta0531
Probable cystathionine gamma-synthase; Strong similarity to known protein: Arabidopsis thaliana gene for cystathionine gamma-synthase, complete cds; TREMBL:AB010888_1Function: Involved in Cysteine metabolism, Methionine metabolism, Glycine, serine and threonine metabolism, Selenoamino acid metabolism. EC Numbers and enzyme names are mixed up, homologs are called cystathionine gamma-synthase (EC 4.2.99.9) and cystathionine gamma lyase (EC 4.4.1.-).
  
 
 0.964
Ta0059
Conserved hypothetical protein; Catalyzes the formation of S-adenosylmethionine from methionine and ATP; Belongs to the AdoMet synthase 2 family.
  
  
 0.928
Ta1162
Probable methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
    
 0.908
Ta1179
Similarity to known protein: HOMOSERINE DEHYDROGENASE (EC 1.1.1.3) (HDH) - Bacillus subtilis; SWISSPROT:DHOM_BACSU.
 
 
 0.904
Ta0848
Strong similarity to unknown protein: conserved hypothetical protein - Thermotoga maritima (strain MSB8); PIR:E72365.
    
  0.900
Ta0113
Strong similarity to known protein: threonine dehydratase (EC 4.2.1.16), biodegradative [validated] - Escherichia coli; PIR:DWECTD.
  
 
 0.851
Your Current Organism:
Thermoplasma acidophilum
NCBI taxonomy Id: 273075
Other names: T. acidophilum DSM 1728, Thermoplasma acidophilum DSM 1728
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