STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ta1157Similarity to known protein: DIHYDRODIPICOLINATE SYNTHASE (EC 4.2.1.52) (DHDPS) - Prochlorococcus marinus; SWISSPROT:DAPA_PROMA. Relation: also similar to 2-keto-3-deoxy gluconate aldolase TREMBL:SSO224174_1; Belongs to the DapA family. (292 aa)    
Predicted Functional Partners:
Ta0809
Probable aldehyde dehydrogenase; NADP-dependent dehydrogenase of the nED (non-phosphorylated Entner-Doudoroff) pathway with highest activity towards glyceraldehydes (e.g. D,L-glyceraldehyde and D-glyceraldehyde), to a lesser extent towards D,L-glyceraldehyde-3-phosphate and glycolaldehyde, but no activity towards aliphatic or aromatic aldehydes.
 
 
 0.928
Ta0619
Probable 2-keto-3-deoxy gluconate aldolase; Strong similarity to known protein: Sulfolobus solfataricus gene encoding 2-keto-3-deoxy gluconate aldolase; TREMBL:SSO224174_1. Relation: shows also similarity to dihydrodipicolinate synthase (EC 4.2.1.52) dapA - Bacillus subtilis, PIR:E46665.
  
  
 
0.922
Ta0788
Diaminopimelate decarboxylase related protein; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
  
 0.922
Ta0085
Conserved hypothetical protein.
    
 0.912
Ta0756
Muconate cycloisomerase related protein; Similarity to known protein: hypothetical 64.0 kD protein in ibpA-gyrB intergenic region - Escherichia coli (strain K-12); PIR:E65171Function: possibly involved in Phenylalanin metabolism.
    
 0.912
Ta0825
Glucose kinase related protein; Similarity to known protein: Bacillus megaterium glk gene; TREMBL:BMGLUCKIN_2.
 
 
 0.911
Ta0810
Strong similarity to known protein: TUNGSTEN-CONTAINING ALDEHYDE FERREDOXIN OXIDOREDUCTASE (EC 1.2.7.-) - Pyrococcus furiosus; SWISSPROT:AOR_PYRFUFunction: involved in aldehyde oxidation.
    
  0.900
Ta0834
Similarity to known protein: TUNGSTEN-CONTAINING ALDEHYDE FERREDOXIN OXIDOREDUCTASE (EC 1.2.7.-) - Pyrococcus furiosus; SWISSPROT:AOR_PYRFU.
    
  0.900
Ta1142
Similarity to known protein: TUNGSTEN-CONTAINING ALDEHYDE FERREDOXIN OXIDOREDUCTASE (EC 1.2.7.-) - Pyrococcus furiosus; SWISSPROT:AOR_PYRFU.
    
  0.900
Ta0313
Triosephosphate isomerase related protein; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 
 0.851
Your Current Organism:
Thermoplasma acidophilum
NCBI taxonomy Id: 273075
Other names: T. acidophilum DSM 1728, Thermoplasma acidophilum DSM 1728
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.