STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ta1270Probable 50S ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. (255 aa)    
Predicted Functional Partners:
Ta0359
Acidic ribosomal protein P0 related protein; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.
 
 
 0.999
Ta0434
Strong similarity to known protein: 50S RIBOSOMAL PROTEIN L18E (HL29) (L19) - Haloarcula marismortui (Halobacterium marismortui); SWISSPROT:R18E_HALMA; Belongs to the eukaryotic ribosomal protein eL18 family.
 
   0.999
Ta1057
Probable 50S ribosomal protein L10; Strong similarity to known protein: Bos taurus ribosomal protein (QM) mRNA, complete cds; TREMBL:AF143815_1; Belongs to the universal ribosomal protein uL16 family.
 
 
 0.999
Ta1250
Similarity to known protein: 60S RIBOSOMAL PROTEIN L28 (L27A) (L29) (YL24) (RP62) - Saccharomyces cerevisiae (Baker's yeast); SWISSPROT:RL28_YEAST.
 
   0.999
Ta1252
Probable 50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
 
 
 0.999
Ta1253
Probable 50S ribosomal protein L19; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family.
 
   0.999
Ta1254
Similarity to known protein: 50S RIBOSOMAL PROTEIN L32E - Sulfolobus acidocaldarius; SWISSPROT:RL32_SULAC; Belongs to the eukaryotic ribosomal protein eL32 family.
 
   0.999
Ta1255
Probable 50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
 
   0.999
Ta1256
Probable 30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.
 
 
 0.999
Ta1258
50S RIBOSOMAL PROTEIN L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
 
 
 0.999
Your Current Organism:
Thermoplasma acidophilum
NCBI taxonomy Id: 273075
Other names: T. acidophilum DSM 1728, Thermoplasma acidophilum DSM 1728
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.