STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ta1330Probable ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. (297 aa)    
Predicted Functional Partners:
Ta0650
Strong similarity to known protein: argininosuccinate synthase (EC 6.3.4.5) - Methanococcus vannielii; PIR:AJMXRV; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
 
 0.998
Ta0791
Probable carbamoyl-phosphate synthase, large subunit; Strong similarity to known protein: carbamoyl-phosphate synthase (glutamine-hydrolyzing) (EC 6.3.5.5) - Bacillus caldolyticus; PIR:I40169.
 
 
 0.993
Ta1350
Probable carbamate kinase; Strong similarity to known protein: CARBAMATE KINASE (EC 2.7.2.2) - Clostridium perfringens; SWISSPROT:ARCC_CLOPEFunction: amino acid fermantation.
  
 0.975
Ta0792
Similarity to known protein: carbamoyl-phosphate synthase, small (or glutamine) subunit (carA) homolog - Archaeoglobus fulgidus; PIR:H69408Function: Urea cycle and metabolism of amino groups, Glutamate metabolism, Arginine and proline metabolism, Nitrogen metabolism; Belongs to the CarA family.
 
   
  0.973
Ta0987
Similarity to known protein: Giardia intestinalis arginine deiminase gene, complete cds; TREMBL:GI49236_1.
 
  
 0.933
Ta0649
Similarity to known protein: argininosuccinate lyase (EC 4.3.2.1) - goose; PIR:JN0486.
 
  
 0.932
Ta0575
Strong similarity to known protein: probable aspartate carbamoyltransferase catalytic chain - Pyrococcus horikoshii; PIR:A71119.
 
  
 
0.824
Ta0574
Probable aspartate carbamoyltransferase, regulatory chain; Involved in allosteric regulation of aspartate carbamoyltransferase.
    
  0.811
Ta1331
Probable succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
  
 0.807
Ta0068
Similarity to known protein: Acinetobacter baumannii DNA for L-2, 4-diaminobutyrate:2-ketoglutarate4-aminotransferase, complete cds; TREMBL:AB001599_1Function: Glutamate metabolism, Alanine and Aspartate metabolism, beta-Alanine metabolism, Propanoate metabolism, Butanoate metabolism; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.768
Your Current Organism:
Thermoplasma acidophilum
NCBI taxonomy Id: 273075
Other names: T. acidophilum DSM 1728, Thermoplasma acidophilum DSM 1728
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.