STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ta1365Conserved hypothetical protein; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. (205 aa)    
Predicted Functional Partners:
Ta0941
GTP-binding protein related protein, GTP1/OBG-family; Similarity to known protein: Homo sapiens GTP-binding protein NGB mRNA, complete cds; TREMBL:AF120334_1.
   
 
 0.953
Ta1243
Similarity to known protein: NUCLEOLAR PROTEIN NOP56 - Homo sapiens (Human); SWISSPROT:NO56_HUMANFunction: probably involved in RNA splicing.
 
 0.953
Ta1040
Strong similarity to known protein: ribosomal protein S8.eR [validated] - Haloarcula marismortui; PIR:S49022.
  
 
 0.952
Ta1366
Probable glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
     
 0.943
Ta0055
Translation initiation factor eIF-6 related protein; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.
  
 
 0.920
Ta1271
50S ribosomal protein L3 related protein; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
  
 
 0.894
Ta0432
Probable 30S ribosomal protein S9; Strong similarity to known protein; Belongs to the universal ribosomal protein uS9 family.
   
   0.892
Ta1250
Similarity to known protein: 60S RIBOSOMAL PROTEIN L28 (L27A) (L29) (YL24) (RP62) - Saccharomyces cerevisiae (Baker's yeast); SWISSPROT:RL28_YEAST.
   
 
 0.884
Ta0433
Probable 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
  
   0.868
Ta1269
Probable 50S ribosomal protein L23; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family.
   
   0.863
Your Current Organism:
Thermoplasma acidophilum
NCBI taxonomy Id: 273075
Other names: T. acidophilum DSM 1728, Thermoplasma acidophilum DSM 1728
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.