Ta0057 protein (Thermoplasma acidophilum) - STRING interaction network

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Ta0057

DNA repair helicase Rad3 related protein; ATP-dependent 5'-3' DNA helicase involved in nucleotide excision repair (NER) of DNA. (602 aa)

Predicted Functional Partners:

Ta1016

0.999

Ta0389

0.993

Ta1030

0.993

Ta0431

0.991

Ta1160

0.991

Ta0390

0.987

Ta0199

0.986

Ta1006

0.980

Ta1035

0.910

Ta0917

0.889

Your Current Organism:

Thermoplasma acidophilum

NCBI taxonomy Id: 273075
Other names: T. acidophilum DSM 1728, Thermoplasma acidophilum DSM 1728

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Ta0057	Ta0199	gene:9571272	gene:9571415	DNA repair helicase Rad3 related protein; ATP-dependent 5'-3' DNA helicase involved in nucleotide excision repair (NER) of DNA.	Probable TATA-box binding protein (TFIID homolog); General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation (By similarity).	0.986
Ta0057	Ta0389	gene:9571272	gene:9571609	DNA repair helicase Rad3 related protein; ATP-dependent 5'-3' DNA helicase involved in nucleotide excision repair (NER) of DNA.	DNA-DIRECTED RNA POLYMERASE CHAIN H related protein; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family.	0.993
Ta0057	Ta0390	gene:9571272	gene:9571610	DNA repair helicase Rad3 related protein; ATP-dependent 5'-3' DNA helicase involved in nucleotide excision repair (NER) of DNA.	Probable DNA-directed RNA polymerase chain B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.987
Ta0057	Ta0431	gene:9571272	gene:9571651	DNA repair helicase Rad3 related protein; ATP-dependent 5'-3' DNA helicase involved in nucleotide excision repair (NER) of DNA.	DNA-directed RNA polymerase, chain N related protein; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoN/eukaryotic RPB10 RNA polymerase subunit family.	0.991
Ta0057	Ta0917	gene:9571272	gene:9572133	DNA repair helicase Rad3 related protein; ATP-dependent 5'-3' DNA helicase involved in nucleotide excision repair (NER) of DNA.	Proliferating cell nuclear antigen (PCNA) related protein; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family.	0.889
Ta0057	Ta1006	gene:9571272	gene:9572225	DNA repair helicase Rad3 related protein; ATP-dependent 5'-3' DNA helicase involved in nucleotide excision repair (NER) of DNA.	Probable transcription-associated protein TFIIS; Strong similarity to known protein: DNA-DIRECTED RNA POLYMERASE SUBUNIT M (EC 2.7.7.6) - Thermococcus celer; SWISSPROT:RPOM_THECE; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	0.980
Ta0057	Ta1016	gene:9571272	gene:9572236	DNA repair helicase Rad3 related protein; ATP-dependent 5'-3' DNA helicase involved in nucleotide excision repair (NER) of DNA.	Similarity to known protein: Saccharomyces cerevisiae DNA helicase (RAD25) gene, complete cds; TREMBL:SCRAD25A_1.	0.999
Ta0057	Ta1030	gene:9571272	gene:9572251	DNA repair helicase Rad3 related protein; ATP-dependent 5'-3' DNA helicase involved in nucleotide excision repair (NER) of DNA.	DNA-dependent RNA polymerase, subunit D related protein; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoD/eukaryotic RPB3 RNA polymerase subunit family.	0.993
Ta0057	Ta1035	gene:9571272	gene:9572256	DNA repair helicase Rad3 related protein; ATP-dependent 5'-3' DNA helicase involved in nucleotide excision repair (NER) of DNA.	DNA repair protein RAD2 related protein; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision rep [...]	0.910
Ta0057	Ta1160	gene:9571272	gene:9572381	DNA repair helicase Rad3 related protein; ATP-dependent 5'-3' DNA helicase involved in nucleotide excision repair (NER) of DNA.	Probable DNA-directed RNA polymerase, chain K (rpok); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family.	0.991
Ta0199	Ta0057	gene:9571415	gene:9571272	Probable TATA-box binding protein (TFIID homolog); General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation (By similarity).	DNA repair helicase Rad3 related protein; ATP-dependent 5'-3' DNA helicase involved in nucleotide excision repair (NER) of DNA.	0.986
Ta0199	Ta0389	gene:9571415	gene:9571609	Probable TATA-box binding protein (TFIID homolog); General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation (By similarity).	DNA-DIRECTED RNA POLYMERASE CHAIN H related protein; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family.	0.998
Ta0199	Ta0390	gene:9571415	gene:9571610	Probable TATA-box binding protein (TFIID homolog); General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation (By similarity).	Probable DNA-directed RNA polymerase chain B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.988
Ta0199	Ta0431	gene:9571415	gene:9571651	Probable TATA-box binding protein (TFIID homolog); General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation (By similarity).	DNA-directed RNA polymerase, chain N related protein; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoN/eukaryotic RPB10 RNA polymerase subunit family.	0.994
Ta0199	Ta0917	gene:9571415	gene:9572133	Probable TATA-box binding protein (TFIID homolog); General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation (By similarity).	Proliferating cell nuclear antigen (PCNA) related protein; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family.	0.504
Ta0199	Ta1006	gene:9571415	gene:9572225	Probable TATA-box binding protein (TFIID homolog); General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation (By similarity).	Probable transcription-associated protein TFIIS; Strong similarity to known protein: DNA-DIRECTED RNA POLYMERASE SUBUNIT M (EC 2.7.7.6) - Thermococcus celer; SWISSPROT:RPOM_THECE; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	0.991
Ta0199	Ta1016	gene:9571415	gene:9572236	Probable TATA-box binding protein (TFIID homolog); General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation (By similarity).	Similarity to known protein: Saccharomyces cerevisiae DNA helicase (RAD25) gene, complete cds; TREMBL:SCRAD25A_1.	0.995
Ta0199	Ta1030	gene:9571415	gene:9572251	Probable TATA-box binding protein (TFIID homolog); General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation (By similarity).	DNA-dependent RNA polymerase, subunit D related protein; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoD/eukaryotic RPB3 RNA polymerase subunit family.	0.992
Ta0199	Ta1035	gene:9571415	gene:9572256	Probable TATA-box binding protein (TFIID homolog); General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation (By similarity).	DNA repair protein RAD2 related protein; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision rep [...]	0.598
Ta0199	Ta1160	gene:9571415	gene:9572381	Probable TATA-box binding protein (TFIID homolog); General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation (By similarity).	Probable DNA-directed RNA polymerase, chain K (rpok); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family.	0.994