STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ta0229acetyl-CoA synthetase related protein; Similarity to known protein: acetate--CoA ligase (EC 6.2.1.1) - Emericella nidulans; PIR:SYASAA. (619 aa)    
Predicted Functional Partners:
Ta0169
Known protein: citrate (si)-synthase (EC 4.1.3.7) - Thermoplasma acidophilum; PIR:YKYT.
  
 0.967
Ta0819
Probable citrate (si)-synthase; Strong similarity to known protein: CITRATE SYNTHASE (EC 4.1.3.7) - Thermoplasma acidophilum; SWISSPROT:CISY_THEAC.
  
 0.967
Ta0439
Piperideine-6-carboxilic acid dehydrogenase related protein; Strong similarity to known protein: Malus domestica mRNA for protein abundantly expressed during apple fruitdevelopment, complete cds; TREMBL:D88434_1. Relation: strong similarity to a protein abundantly expressed during apple fruit development, function not known, TREMBL:D88434_1.
  
 0.950
Ta1153
Probable acetyl-CoA synthetase; Strong similarity to known protein: Giardia intestinalis acetyl-CoA synthetase gene, complete cds; TREMBL:AF107206_1.
    
 0.929
Ta1436
Probable lipoamide acyltransferase; Strong similarity to known protein: Myxococcus xanthus lipoic acid synthetase precursor, lipoamideacyltransferase, and lipoate-protein ligase B genes, complete cds; andunknown genes; TREMBL:AF153678_2.
  
 
 0.925
Ta0626
Strong similarity to known protein: PYRUVATE/KETOISOVALERATE OXIDOREDUCTASES COMMON GAMMA SUBUNIT[INCLUDES: PYRUVATE SYNTHASE SUBUNIT PORC (EC 1.2.7.1) (PYRUVATEOXIDOREDUCTASE GAMMA CHAIN) (POR) (PYRUVIC-FERREDOXIN OXIDOREDUCTASEGAMMA SUBUNIT); KETOISOVALERATE OXIDOREDUCTASE SUBUNIT VORC(EC 1.-.-.-) (VOR) (2-OXOISOVALERATE OXIDOREDUCTASE GAMMA CHAIN) (2-OXOISOVALERATE-FERREDOXIN OXIDOREDUCTASE GAMMA SUBUNIT)] - Pyrococcus furiosus; SWISSNEW:PORC_PYRFUFunction: Pyruvate metabolism, Propanoate metabolism, Butanoate metabolism, Reductive carboxylate cycle (CO2 fixation).
  
 
 0.923
Ta1508
Probable SA protein; Strong similarity to known protein: Mus musculus SA mRNA, complete cds; TREMBL:AB022340_1.
 
 
 
0.922
Ta0259
Probable pyruvate ferredoxin oxidoreductase, alpha subunit; Strong similarity to known protein: 2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain [validated] - Sulfolobus sp. (strain 7); PIR:JC4919.
  
 
 0.918
Ta0773
Strong similarity to known protein: 2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain [validated] - Sulfolobus sp. (strain 7); PIR:JC4919.
  
 
 0.918
Ta0421
Probable acetyl-coenzyme-A synthetase; Strong similarity to known protein: acetate--CoA ligase (EC 6.2.1.1) [validated] - Methanothrix soehngenii; PIR:A41043.
 
 
 
0.916
Your Current Organism:
Thermoplasma acidophilum
NCBI taxonomy Id: 273075
Other names: T. acidophilum DSM 1728, Thermoplasma acidophilum DSM 1728
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.