STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ta0258Probable fumarase; Strong similarity to known protein: Bacillus subtilis 42.7kB DNA fragment from yvsA to yvqA; TREMBLNEW:BS43KBDNA_39. (457 aa)    
Predicted Functional Partners:
Ta1001
Probable fumarate reductase (frdA); Strong similarity to known protein: S.acidocaldarius sdhA, sdhB, sdhC and sdhD genes; TREMBL:SASDHABCD_2.
 
 
 0.992
Ta1002
Probable fumarate reductase, subunit B; Strong similarity to known protein: FUMARATE REDUCTASE IRON-SULFUR PROTEIN (EC 1.3.99.1) - Proteus vulgaris; SWISSPROT:FRDB_PROVU.
  
 
 0.942
Ta0456
Malate oxidoreductase (malic enzyme) related protein; Similarity to known protein: malate dehydrogenase (oxaloacetate-decarboxylating) (EC 1.1.1.38) - Bacillus stearothermophilus; PIR:DEBSXS.
  
 
 0.927
Ta1003
Known protein: probable cytochrome b, diheme - Thermoplasma acidophilum; PIR:S34620.
  
  0.924
Ta0952
Probable malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily.
    
 0.915
Ta1004
Succinate dehydrogenase, subunit D; Membrane-anchoring subunit of succinate dehydrogenase (SDH).
     
 0.906
Ta0972
L-asparaginase related protein; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
 
  
 0.871
Ta0425
Similarity to known protein: formate dehydrogenase (EC 1.2.1.2) H (hydrogenase-linked) - Escherichia coli; PIR1:DEECFS.
  
 
 0.839
Ta0529
Probable aspartate aminotransferase; Strong similarity to known protein: aspartate transaminase (EC 2.6.1.1) - Sulfolobus solfataricus; PIR:S07088Function: Glutamate metabolism, Alanine and Aspartate metabolism Cysteine metabolism, Carbon fixation.
    
 0.836
Ta0169
Known protein: citrate (si)-synthase (EC 4.1.3.7) - Thermoplasma acidophilum; PIR:YKYT.
    
 0.834
Your Current Organism:
Thermoplasma acidophilum
NCBI taxonomy Id: 273075
Other names: T. acidophilum DSM 1728, Thermoplasma acidophilum DSM 1728
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