Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Ta0063 | Ta0158 | gene:9571278 | gene:9571373 | DNA topoisomerase III beta related protein; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, [...] | Conserved hypothetical protein; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity. Belongs to the MRE11/RAD32 family. | 0.842 |
| Ta0063 | Ta0387 | gene:9571278 | gene:9571606 | DNA topoisomerase III beta related protein; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, [...] | Similarity to unknown protein: hypothetical protein MJ1159 - Methanococcus jannaschii; PIR:F64444. | 0.855 |
| Ta0063 | Ta0907 | gene:9571278 | gene:9572122 | DNA topoisomerase III beta related protein; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, [...] | DNA polymerase (PolB), large chain related protein; Similarity to known protein: Pyrococcus sp. Deep Vent DNA polymerase precursor gene, complete cds; TREMBL:P707_2ORF_prediction: This ORF does not include an intein, as e.g. the related DNA-dependent DNA polymerase precursor from Thermococcus litoralis. | 0.527 |
| Ta0063 | Ta0917 | gene:9571278 | gene:9572133 | DNA topoisomerase III beta related protein; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, [...] | Proliferating cell nuclear antigen (PCNA) related protein; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family. | 0.738 |
| Ta0063 | Ta1036 | gene:9571278 | gene:9572257 | DNA topoisomerase III beta related protein; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, [...] | DNA repair protein RAD51 related protein; Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange (By similarity). | 0.763 |
| Ta0063 | Ta1104 | gene:9571278 | gene:9572325 | DNA topoisomerase III beta related protein; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, [...] | Probable DNA repair protein Rad51 (RadA); Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules (By similarity). | 0.763 |
| Ta0063 | Ta1149 | gene:9571278 | gene:9572370 | DNA topoisomerase III beta related protein; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, [...] | Similarity to unknown protein: hypothetical protein APE1323 - Aeropyrum pernix (strain K1); PIR:E72607. | 0.821 |
| Ta0158 | Ta0063 | gene:9571373 | gene:9571278 | Conserved hypothetical protein; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity. Belongs to the MRE11/RAD32 family. | DNA topoisomerase III beta related protein; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, [...] | 0.842 |
| Ta0158 | Ta0387 | gene:9571373 | gene:9571606 | Conserved hypothetical protein; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity. Belongs to the MRE11/RAD32 family. | Similarity to unknown protein: hypothetical protein MJ1159 - Methanococcus jannaschii; PIR:F64444. | 0.835 |
| Ta0158 | Ta0907 | gene:9571373 | gene:9572122 | Conserved hypothetical protein; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity. Belongs to the MRE11/RAD32 family. | DNA polymerase (PolB), large chain related protein; Similarity to known protein: Pyrococcus sp. Deep Vent DNA polymerase precursor gene, complete cds; TREMBL:P707_2ORF_prediction: This ORF does not include an intein, as e.g. the related DNA-dependent DNA polymerase precursor from Thermococcus litoralis. | 0.582 |
| Ta0158 | Ta0917 | gene:9571373 | gene:9572133 | Conserved hypothetical protein; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity. Belongs to the MRE11/RAD32 family. | Proliferating cell nuclear antigen (PCNA) related protein; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family. | 0.558 |
| Ta0158 | Ta1036 | gene:9571373 | gene:9572257 | Conserved hypothetical protein; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity. Belongs to the MRE11/RAD32 family. | DNA repair protein RAD51 related protein; Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange (By similarity). | 0.787 |
| Ta0158 | Ta1104 | gene:9571373 | gene:9572325 | Conserved hypothetical protein; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity. Belongs to the MRE11/RAD32 family. | Probable DNA repair protein Rad51 (RadA); Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules (By similarity). | 0.811 |
| Ta0158 | Ta1149 | gene:9571373 | gene:9572370 | Conserved hypothetical protein; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity. Belongs to the MRE11/RAD32 family. | Similarity to unknown protein: hypothetical protein APE1323 - Aeropyrum pernix (strain K1); PIR:E72607. | 0.835 |
| Ta0387 | Ta0063 | gene:9571606 | gene:9571278 | Similarity to unknown protein: hypothetical protein MJ1159 - Methanococcus jannaschii; PIR:F64444. | DNA topoisomerase III beta related protein; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, [...] | 0.855 |
| Ta0387 | Ta0158 | gene:9571606 | gene:9571373 | Similarity to unknown protein: hypothetical protein MJ1159 - Methanococcus jannaschii; PIR:F64444. | Conserved hypothetical protein; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity. Belongs to the MRE11/RAD32 family. | 0.835 |
| Ta0387 | Ta0388 | gene:9571606 | gene:9571607 | Similarity to unknown protein: hypothetical protein MJ1159 - Methanococcus jannaschii; PIR:F64444. | Weak similarity to unknown protein. | 0.988 |
| Ta0387 | Ta0799 | gene:9571606 | gene:9572014 | Similarity to unknown protein: hypothetical protein MJ1159 - Methanococcus jannaschii; PIR:F64444. | DNA replication licensing factor MCM related protein; Similarity to known protein: CDC21 PROTEIN.CDC21 PROTEIN - Schizosaccharomyces pombe (Fission yeast).Schizosaccharomyces pombe (Fission yeast); SWISSPROT:CC21_SCHPO; Belongs to the MCM family. | 0.880 |
| Ta0387 | Ta0907 | gene:9571606 | gene:9572122 | Similarity to unknown protein: hypothetical protein MJ1159 - Methanococcus jannaschii; PIR:F64444. | DNA polymerase (PolB), large chain related protein; Similarity to known protein: Pyrococcus sp. Deep Vent DNA polymerase precursor gene, complete cds; TREMBL:P707_2ORF_prediction: This ORF does not include an intein, as e.g. the related DNA-dependent DNA polymerase precursor from Thermococcus litoralis. | 0.803 |
| Ta0387 | Ta0917 | gene:9571606 | gene:9572133 | Similarity to unknown protein: hypothetical protein MJ1159 - Methanococcus jannaschii; PIR:F64444. | Proliferating cell nuclear antigen (PCNA) related protein; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family. | 0.940 |
page 1 of 4