STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ta0468Probable seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (441 aa)    
Predicted Functional Partners:
Ta0673
Weak similarity to known protein. Relation: weak similarity to seryl-tRNA(Ser) selenium transferase (EC 2.9.1.1) - Escherichia coli, PIR:A65159.
    
 0.944
Ta0281
Similarity to known protein: arginine--tRNA ligase (EC 6.1.1.19) - Corynebacterium glutamicum; PIR1:A49936; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
 
 0.883
Ta1211
tryptophanyl-tRNA synthetase related protein; Similarity to known protein: H.sapiens mRNA for IFP53; TREMBL:HSIFP53_1; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 
 0.866
Ta0040
valyl-tRNA synthetase related protein; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
 
  
 0.854
Ta0512
Probable tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 4 subfamily.
 
  
 0.826
Ta1147
Probable cysteinyl-tRNA synthetase; Strong similarity to known protein: E. coli cysS gene for cysteinyl-tRNA synthetase; TREMBL:ECCYSSG_1.
 
 
 0.826
Ta0206
Similarity to known protein: GLYCYL-TRNA SYNTHETASE (EC 6.1.1.14) (GLYCINE--TRNA LIGASE) (GLYRS) - Arabidopsis thaliana (Mouse-ear cress); SWISSPROT:SYG_ARATH.
   
  
 0.806
Ta0330
threonine--tRNA ligase related protein; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).
 
 
 0.774
Ta0984
Strong similarity to known protein: THIOREDOXIN REDUCTASE (EC 1.6.4.5) (TRXR) - Listeria monocytogenes; SWISSPROT:TRXB_LISMO.
 
  
 0.767
Ta1030
DNA-dependent RNA polymerase, subunit D related protein; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoD/eukaryotic RPB3 RNA polymerase subunit family.
 
  
 0.763
Your Current Organism:
Thermoplasma acidophilum
NCBI taxonomy Id: 273075
Other names: T. acidophilum DSM 1728, Thermoplasma acidophilum DSM 1728
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.