STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ta0576Similarity to known protein: protoporphyrin IX magnesium chelatase (EC 4.99.1.-) ChlI - Methanobacterium thermoautotrophicum (strain Delta H); PIR:E69173. (617 aa)    
Predicted Functional Partners:
Ta0311
Ferrochelatase related protein; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
  
 
 0.934
Ta1495
Similarity to known protein: Arabidopsis thaliana mRNA for geranylgeranyl reductase; TREMBL:ATGGREDU_1.
 
  
 0.730
Ta0516
Geranylgeranyl reductase related protein; Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3- diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di- O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains. Can use both NADH and NADPH as electron donors. Also catalyzes the reduction of the naturally occurring 2,3-di-O-geranylgeranylgly [...]
 
  
 0.701
Ta0572
Porphobilinogen deaminase related protein; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
  
  
 0.672
Ta0654
Similarity to known protein: PRECORRIN-8X METHYLMUTASE (EC 5.4.1.2) (PRECORRIN ISOMERASE) - Salmonella typhimurium; SWISSPROT:CBIC_SALTYORF_prediction: This ORF might be 33 aa longer, however, codon usage and frequency of rare codons support the current gene prediction.
 
   
 0.631
Ta0575
Strong similarity to known protein: probable aspartate carbamoyltransferase catalytic chain - Pyrococcus horikoshii; PIR:A71119.
       0.618
Ta0574
Probable aspartate carbamoyltransferase, regulatory chain; Involved in allosteric regulation of aspartate carbamoyltransferase.
       0.607
Ta1200
Probable cobyrinic acid a, c-diamide synthase (cbiA); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
     
 0.570
Ta0996
Strong similarity to unknown protein: conserved hypothetical protein MJ0279 - Methanococcus jannaschii; PIR:H64334.
 
  
 0.565
Ta0655
Probable cobalamin biosynthesis precorrin-3 methylase; Similarity to known protein: Bacillus megaterium 16kb genomic sequence, cobalamin operon; TREMBL:BMAJ758_2.
 
   
 0.549
Your Current Organism:
Thermoplasma acidophilum
NCBI taxonomy Id: 273075
Other names: T. acidophilum DSM 1728, Thermoplasma acidophilum DSM 1728
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