STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ta0582Strong similarity to known protein: acetyl-CoA C-acetyltransferase (EC 2.3.1.9) [validated] - Clostridium acetobutylicum; PIR:JC4032. (388 aa)    
Predicted Functional Partners:
Ta0476
Strong similarity to known protein: Sus scrofa L-3-hydroxyacyl-CoA dehydrogenase precursor (HAD) mRNA, nucleargene encoding mitochondrial protein, complete cds; TREMBL:AF027652_1Function: Fatty acid biosynthesis (path 2), Fatty acid metabolism, Valine, leucine and isoleucine degradation, Lysine degradation, Tryptophan metabolism, Butanoate metabolism.
 
 0.994
Ta0947
Similarity to known protein: beta-hydroxybutyryl-CoA dehydrogenase, NAD-dependent (EC 1.1.1.-) - Clostridium acetobutylicum; PIR:A43723Function: poly beta-hydroxybutyrate biosynthesis.
 
 0.988
Ta1455
Conserved hypothetical protein; Strong similarity to unknown protein: acyl carrier protein synthase - Methanococcus jannaschii; PIR:A64493; Belongs to the thiolase-like superfamily. UPF0219 family.
  
 0.988
Ta0291
Similarity to known protein: Rattus norvegicus L-3-hydroxyacyl-CoA dehydrogenase precursor (HAD) mRNA, complete cds; nuclear gene for mitochondrial product; TREMBL:AF095449_1.
 
 0.984
Ta0398
Similarity to known protein: ACYL-COA DEHYDROGENASE, SHORT-CHAIN SPECIFIC (EC 1.3.99.2)(SCAD) (BUTYRYL-COA DEHYDROGENASE) - Clostridium acetobutylicum; SWISSPROT:ACDS_CLOABFunction: Fatty acid metabolism, Valine, leucine and isoleucine degradation, beta-Alanine metabolism, Propanoate metabolism.
  
 0.960
Ta0169
Known protein: citrate (si)-synthase (EC 4.1.3.7) - Thermoplasma acidophilum; PIR:YKYT.
  
 0.938
Ta0819
Probable citrate (si)-synthase; Strong similarity to known protein: CITRATE SYNTHASE (EC 4.1.3.7) - Thermoplasma acidophilum; SWISSPROT:CISY_THEAC.
  
 0.938
Ta1436
Probable lipoamide acyltransferase; Strong similarity to known protein: Myxococcus xanthus lipoic acid synthetase precursor, lipoamideacyltransferase, and lipoate-protein ligase B genes, complete cds; andunknown genes; TREMBL:AF153678_2.
  
 
 0.925
Ta1153
Probable acetyl-CoA synthetase; Strong similarity to known protein: Giardia intestinalis acetyl-CoA synthetase gene, complete cds; TREMBL:AF107206_1.
  
 
 0.920
Ta0406
Similarity to known protein: hydroxymethylglutaryl-CoA reductase (EC 1.1.1.88) - Pseudomonas sp; PIR:A44756.
 
  
 0.913
Your Current Organism:
Thermoplasma acidophilum
NCBI taxonomy Id: 273075
Other names: T. acidophilum DSM 1728, Thermoplasma acidophilum DSM 1728
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.