STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ta0659Probable precorrin-4 methylase; Strong similarity to known protein: Bacillus megaterium 16kb genomic sequence, cobalamin operon; TREMBL:BMAJ758_9; Belongs to the precorrin methyltransferase family. (255 aa)    
Predicted Functional Partners:
Ta0655
Probable cobalamin biosynthesis precorrin-3 methylase; Similarity to known protein: Bacillus megaterium 16kb genomic sequence, cobalamin operon; TREMBL:BMAJ758_2.
 
0.999
Ta0658
Similarity to known protein: precorrin-2 methyltransferase (EC 2.1.1.-) - Pseudomonas sp; PIR:D36145.
  
0.999
Ta0654
Similarity to known protein: PRECORRIN-8X METHYLMUTASE (EC 5.4.1.2) (PRECORRIN ISOMERASE) - Salmonella typhimurium; SWISSPROT:CBIC_SALTYORF_prediction: This ORF might be 33 aa longer, however, codon usage and frequency of rare codons support the current gene prediction.
 
  
 0.997
Ta0660
Weak similarity to known protein. Relation: weak simmilarity to uroporphyrin-III C-methyltransferase (EC 2.1.1.107) - maize, PIR:T03269.
  
0.997
Ta0657
precorrin-8W decarboxylase related protein; Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin-7.
 
  
 0.993
Ta0075
COBYRIC ACID SYNTHASE related protein; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity); Belongs to the CobB/CobQ family. CobQ subfamily.
  
  
 0.978
Ta0656
Cobalamin biosynthesis protein D related protein; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
 
  
 0.976
Ta0572
Porphobilinogen deaminase related protein; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
   
 0.951
Ta1200
Probable cobyrinic acid a, c-diamide synthase (cbiA); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
  
 0.833
Ta0021
Similarity to known protein: HISTIDINOL-PHOSPHATE AMINOTRANSFERASE (EC 2.6.1.9) (IMIDAZOLE ACETOL-PHOSPHATE TRANSAMINASE) - Salmonella typhimurium; SWISSPROT:HIS8_SALTY.
  
 0.811
Your Current Organism:
Thermoplasma acidophilum
NCBI taxonomy Id: 273075
Other names: T. acidophilum DSM 1728, Thermoplasma acidophilum DSM 1728
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