STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ta0674Conserved hypothetical protein; Weak similarity to unknown protein. (275 aa)    
Predicted Functional Partners:
Ta0897
Glucose 1-dehydrogenase; Catalyzes the NAD(P)(+)-dependent oxidation of D-glucose to D-gluconate via gluconolactone. Is also significantly active with galactose as substrate, but not with mannose or glucose 6-phosphate. Can utilize both NAD(+) and NADP(+) as electron acceptor, with a marked preference for NADP(+). Physiologically, may be involved in the degradation of both glucose and galactose through a non-phosphorylative variant of the Entner-Doudoroff pathway; Belongs to the zinc-containing alcohol dehydrogenase family. Glucose 1-dehydrogenase subfamily.
 
 
 0.945
Ta1323
Strong similarity to known protein: beta-galactosidase (EC 3.2.1.23) - Sulfolobus solfataricus; PIR:S06762. Relation: Beta-glycosidase scop domains score better than beta-galactosidase domains, thus the protein may be a beta-glycosidase. Title and functional predictions follow the closest experimentally characterized homolog, therefore beta-galactosidase attributes prevail; Belongs to the glycosyl hydrolase 1 family.
 
 
 0.939
Ta0825
Glucose kinase related protein; Similarity to known protein: Bacillus megaterium glk gene; TREMBL:BMGLUCKIN_2.
  
 
 0.925
Ta0911
Similarity to unknown protein: hypothetical 34K protein (glnA-fdhE intergenic region) - Escherichia coli; PIR:S40823.
  
  
 
0.910
Ta0672
Similarity to known protein: polyketide synthase (EC 2.-.-.-) chain 7 - Actinomadura hibisca; PIR:JC5856.
  
  
 0.793
Ta0671
Hypothetical protein; No similarity. Relation: weak similarity to amino acid transporter homolog ybeC - Bacillus subtilis, PIR:D69748.
       0.774
Ta0673
Weak similarity to known protein. Relation: weak similarity to seryl-tRNA(Ser) selenium transferase (EC 2.9.1.1) - Escherichia coli, PIR:A65159.
       0.774
Ta0675
Conserved hypothetical protein; Weak similarity to unknown protein.
       0.494
Ta0507
Similarity to unknown protein: hypothetical protein APE0237 - Aeropyrum pernix (strain K1); PIR:D72781.
  
     0.458
Ta0140
Conserved hypothetical protein; Weak similarity to known protein. Relation: weak similarity to CYTOCHROME B6-F COMPLEX IRON-SULFUR SUBUNIT, Chlorobium limicola, SWISSPROT:UCRI_CHLLT; Belongs to the SDX family.
 
     0.440
Your Current Organism:
Thermoplasma acidophilum
NCBI taxonomy Id: 273075
Other names: T. acidophilum DSM 1728, Thermoplasma acidophilum DSM 1728
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