STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ta0920Similarity to known protein: methanol dehydrogenase regulatory protein moxR [validated] - Paracoccus denitrificans; PIR:D41377. (319 aa)    
Predicted Functional Partners:
Ta0919
Similarity to unknown protein: hypothetical protein slr2013 - Synechocystis sp. (strain PCC 6803); PIR:S75346.
 
  
 0.965
Ta0922
Weak similarity to unknown protein.
       0.826
Ta0918
Conserved hypothetical membrane protein; Weak similarity to known protein.
       0.792
Ta0921
Weak similarity to unknown protein.
       0.787
Ta0917
Proliferating cell nuclear antigen (PCNA) related protein; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family.
  
    0.679
Ta0861
Similarity to known protein: heat shock protein htpX - Escherichia coli; PIR:A43659; Belongs to the peptidase M48B family.
  
    0.611
Ta0456
Malate oxidoreductase (malic enzyme) related protein; Similarity to known protein: malate dehydrogenase (oxaloacetate-decarboxylating) (EC 1.1.1.38) - Bacillus stearothermophilus; PIR:DEBSXS.
  
    0.583
Ta0923
Weak similarity to unknown protein.
       0.567
Ta0311
Ferrochelatase related protein; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
     
 0.511
Ta1086
Heat shock protein GrpE related protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Severa [...]
   
 
 0.464
Your Current Organism:
Thermoplasma acidophilum
NCBI taxonomy Id: 273075
Other names: T. acidophilum DSM 1728, Thermoplasma acidophilum DSM 1728
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.