STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ta0936Conserved hypothetical protein; Weak similarity to known protein. Relation: similar to phosphoserine phosphatase PIR:S53931. (212 aa)    
Predicted Functional Partners:
Ta1509
Probable glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
 
 0.947
Ta0811
Similarity to known protein: glycine hydroxymethyltransferase (EC 2.1.2.1) - Methanobacterium thermoautotrophicum (strain Marburg); PIR:S62190Function: involved in glycine, serine and threonine metabolism, also involved in vitamin B6 metabolism.
 
 0.943
Ta0113
Strong similarity to known protein: threonine dehydratase (EC 4.2.1.16), biodegradative [validated] - Escherichia coli; PIR:DWECTD.
    
 0.918
Ta0669
Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
 
  
  0.913
Ta0803
Similarity to known protein: TRYPTOPHAN SYNTHASE ALPHA CHAIN (EC 4.2.1.20).TRYPTOPHAN SYNTHASE ALPHA CHAIN (EC 4.2.1.20) - Sulfolobus solfataricus.Sulfolobus solfataricus; SWISSPROT:TRPA_SULSO.
  
 
 0.909
Ta0937
prolyl-tRNA synthetase related protein; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
  
  
 0.890
Ta0021
Similarity to known protein: HISTIDINOL-PHOSPHATE AMINOTRANSFERASE (EC 2.6.1.9) (IMIDAZOLE ACETOL-PHOSPHATE TRANSAMINASE) - Salmonella typhimurium; SWISSPROT:HIS8_SALTY.
  
  
 0.659
Ta0998
Conserved hypothetical protein; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency; Belongs to the THEP1 NTPase family.
 
     0.447
Ta0309
Similarity to known protein: PHOSPHORIBOSYLAMIDOIMIDAZOLE-SUCCINOCARBOXAMIDE SYNTHASE (EC 6.3.2.6)(SAICAR SYNTHETASE) - Saccharomyces cerevisiae (Baker's yeast); SWISSPROT:PUR7_YEAST.
 
 
 0.423
Ta0350
Similarity to unknown protein: hypothetical protein APE1894 - Aeropyrum pernix (strain K1); PIR:F72576.
 
     0.419
Your Current Organism:
Thermoplasma acidophilum
NCBI taxonomy Id: 273075
Other names: T. acidophilum DSM 1728, Thermoplasma acidophilum DSM 1728
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.