STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ta1003Known protein: probable cytochrome b, diheme - Thermoplasma acidophilum; PIR:S34620. (130 aa)    
Predicted Functional Partners:
Ta0965
NADH dehydrogenase, chain ndhI; Similarity to known protein: NADH dehydrogenase (ubiquinone) (EC 1.6.5.3) chain ndhI - Synechocystis sp. (strain PCC 6803); PIR:FEYBQI.
  
  
 0.999
Ta1001
Probable fumarate reductase (frdA); Strong similarity to known protein: S.acidocaldarius sdhA, sdhB, sdhC and sdhD genes; TREMBL:SASDHABCD_2.
  
 0.999
Ta1002
Probable fumarate reductase, subunit B; Strong similarity to known protein: FUMARATE REDUCTASE IRON-SULFUR PROTEIN (EC 1.3.99.1) - Proteus vulgaris; SWISSPROT:FRDB_PROVU.
  
 0.999
Ta1004
Succinate dehydrogenase, subunit D; Membrane-anchoring subunit of succinate dehydrogenase (SDH).
  
 0.999
Ta1332
Probable succinyl-CoA synthetase, beta subunit; Strong similarity to known protein: succinate--CoA ligase (ADP-forming) (EC 6.2.1.5) beta chain [validated] - Thermus aquaticus; PIR:S15950.
  
 
 0.998
Ta1331
Probable succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 
 0.995
Ta0967
Probable NADH dehydrogenase, chain D; Strong similarity to known protein: NADH-UBIQUINONE OXIDOREDUCTASE 49 KDA SUBUNIT PRECURSOR (EC 1.6.5.3)(EC 1.6.99.3) (COMPLEX I-49KD) (CI-49KD) - Homo sapiens (Human); SWISSPROT:NUCM_HUMAN.
  
 
 0.985
Ta0968
Similarity to known protein: NADH DEHYDROGENASE I CHAIN C (EC 1.6.5.3) (NADH-UBIQUINONEOXIDOREDUCTASE CHAIN 3) (NUO3) - Escherichia coli; SWISSPROT:NUOC_ECOLI.
  
  
 0.952
Ta0258
Probable fumarase; Strong similarity to known protein: Bacillus subtilis 42.7kB DNA fragment from yvsA to yvqA; TREMBLNEW:BS43KBDNA_39.
  
  0.924
Ta0969
Probable NADH dehydrogenase, chain B; Strong similarity to known protein: NADH dehydrogenase (ubiquinone) (EC 1.6.5.3) chain NQO6 - Thermus aquaticus thermophilus; PIR:T11899; Belongs to the complex I 20 kDa subunit family.
  
  
 0.908
Your Current Organism:
Thermoplasma acidophilum
NCBI taxonomy Id: 273075
Other names: T. acidophilum DSM 1728, Thermoplasma acidophilum DSM 1728
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.