STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ta1178ABC transporter, ATP-binding protein related protein; Similarity to known protein: NITRATE TRANSPORT PROTEIN NASD - Klebsiella pneumoniae; SWISSPROT:NASD_KLEPN. (272 aa)    
Predicted Functional Partners:
Ta1177
Hypothetical membrane protein; Weak similarity to known proteinORF_prediction: Presence of protein splicing possible, but not predictable., possible location of the Intein aa 186-400.
 
   
 0.983
Ta1176
Hypothetical protein.
 
     0.892
Ta1396
Hypothetical protein.
  
  
 0.649
Ta0460
Endonuclease V related protein; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA (By similarity); In the N-terminal section; belongs to the MGMT family.
       0.597
Ta0652
Hypothetical protein.
 
     0.518
Ta1179
Similarity to known protein: HOMOSERINE DEHYDROGENASE (EC 1.1.1.3) (HDH) - Bacillus subtilis; SWISSPROT:DHOM_BACSU.
       0.490
Ta1485
Weak similarity to unknown protein. Relation: weak similarity to TenA von B. subtilis.
  
    0.465
Ta1277
Thiamine phosphate pyrophosphorylase (yeast THI6) related protein; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
  
    0.452
Ta0847
Strong similarity to unknown protein: conserved hypothetical protein MJ1052 - Methanococcus jannaschii; PIR:C64431.
  
  
 0.443
Ta0653
S-adenosyl-L-methionine uroporphyrinogen methyltransferase related protein; Similarity to known protein: uroporphyrin-III C-methyltransferase (EC 2.1.1.107) [validated] - Methanobacterium ivanovii; PIR:A42471.
       0.426
Your Current Organism:
Thermoplasma acidophilum
NCBI taxonomy Id: 273075
Other names: T. acidophilum DSM 1728, Thermoplasma acidophilum DSM 1728
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.