STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ta1301Similarity to known protein: membrane protein 7, erythrocyte - human; PIR2:S17659. (274 aa)    
Predicted Functional Partners:
Ta1083
Similarity to known protein: Rhizobium etli plasmid pTAL182c NfeD (nfeD) gene, complete cds; TREMBLNEW:RE41754_1.
 
  
 0.834
Ta1060
Similarity to known protein: ATRAZINE CHLOROHYDROLASE (EC 3.8.1.-) - Pseudomonas sp. (strain ADP); SWISSPROT:ATZA_PSESDFunction: FIRST STEP IN ATRAZINE DEGRADATION PATHWAY.
 
  
 0.832
Ta1087
Probable DnaK-type molecular chaperone; Acts as a chaperone.
  
 0.683
Ta0037
Similarity to unknown protein: conserved hypothetical protein AF2209 - Archaeoglobus fulgidus; PIR:A69526.
  
 0.658
Ta1192
Hypothetical GTP-binding protein; Weak similarity to known protein.
  
 0.658
Ta1045
Similarity to known protein: PLASMA MEMBRANE ATPASE 3 (EC 3.6.1.35) (PROTON PUMP).PLASMA MEMBRANE ATPASE 3 (EC 3.6.1.35) (PROTON PUMP 3) - Arabidopsis thaliana (Mouse-ear cress).Arabidopsis thaliana (Mouse-ear cress); SWISSPROT:PMA3_ARATH.
  
 0.566
Ta1086
Heat shock protein GrpE related protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Severa [...]
  
 
 0.557
Ta0279
Strong similarity to unknown protein: conserved hypothetical protein AF0862 - Archaeoglobus fulgidus; PIR:F69357; Belongs to the RtcB family.
  
   0.546
Ta0113
Strong similarity to known protein: threonine dehydratase (EC 4.2.1.16), biodegradative [validated] - Escherichia coli; PIR:DWECTD.
  
 
 0.524
Ta1059
Translation initiation factor eIF-5a related protein; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.
  
 
 0.515
Your Current Organism:
Thermoplasma acidophilum
NCBI taxonomy Id: 273075
Other names: T. acidophilum DSM 1728, Thermoplasma acidophilum DSM 1728
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.