STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ta1349Similarity to unknown protein: conserved hypothetical protein - Thermotoga maritima (strain MSB8); PIR:E72235. Relation: weak similarity to plasma-cell membrane glycoprotein pc-1 - human, SWISSPROT:PC1_HUMAN. (421 aa)    
Predicted Functional Partners:
Ta0460
Endonuclease V related protein; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA (By similarity); In the N-terminal section; belongs to the MGMT family.
 
     0.837
Ta1350
Probable carbamate kinase; Strong similarity to known protein: CARBAMATE KINASE (EC 2.7.2.2) - Clostridium perfringens; SWISSPROT:ARCC_CLOPEFunction: amino acid fermantation.
       0.564
Ta0298
Similarity to known protein: ALPHA-GLUCOSIDASE (EC 3.2.1.20) (MALTASE).ALPHA-GLUCOSIDASE (EC 3.2.1.20) (MALTASE) - Sulfolobus solfataricus.Sulfolobus solfataricus; SWISSPROT:AGLU_SULSO; Belongs to the glycosyl hydrolase 31 family.
   
 0.500
Ta0285
3-dehyroquinate synthase related protein; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
 
     0.497
Ta0905
Similarity to known protein: GTP-binding protein obg - Bacillus subtilis; PIR:B32804.
 
     0.496
Ta1214
Similarity to known protein: Canarypox virus gene for thymidine kinase and 8 ORFs, partial and completecds; TREMBL:D86731_5.
  
    0.444
Ta0039
Weak similarity to known protein.
       0.426
Ta1054
DNA gyrase, subunit A (gyrA) related protein; Similarity to known protein: DNA topoisomerase (ATP-hydrolyzing) (EC 5.99.1.3) chain A - Haloferax sp; PIR:S30571.
       0.426
Ta1153
Probable acetyl-CoA synthetase; Strong similarity to known protein: Giardia intestinalis acetyl-CoA synthetase gene, complete cds; TREMBL:AF107206_1.
       0.426
Ta1380
Conserved hypothetical protein; Involved in DNA damage repair.
       0.426
Your Current Organism:
Thermoplasma acidophilum
NCBI taxonomy Id: 273075
Other names: T. acidophilum DSM 1728, Thermoplasma acidophilum DSM 1728
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.