STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TVG0090326Formate-tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. (536 aa)    
Predicted Functional Partners:
TVG0091933
Formiminotransferase cyclodeaminase.
    
 0.990
TVG1072456
Methylene-tetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
   
 0.990
TVG0015470
Phosphoribosylaminoimidazole carboxamide formyl transferase/IMP cyclo-hydrolase.
  
 0.982
TVG0180390
Phosphoribosylglycinamide formyltransferase.
  
 0.967
TVG0092631
Hypothetical protein.
    
 0.964
TVG0048225
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 0.962
TVG0811706
Serine hydroxymethyltransferase.
  
 0.961
TVG0060439
Aminomethyltransferase.
  
 0.948
TVG1355049
Phosphoribosylaminoimidazole succinocarboxyamide synthase; Belongs to the SAICAR synthetase family.
  
 
 0.816
TVG0348801
Amidophosphoribosyl transferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
  
  
 0.740
Your Current Organism:
Thermoplasma volcanium
NCBI taxonomy Id: 273116
Other names: T. volcanium GSS1, Thermoplasma volcanium GSS1, Thermoplasma volcanium str. GSS1, Thermoplasma volcanium strain GSS1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.