node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
UU489 | UU580 | UU489 | UU580 | Unique hypothetical membrane lipoprotein. | Unique hypothetical; Belongs to the SecE/SEC61-gamma family. | 0.999 |
UU489 | secA | UU489 | UU119 | Unique hypothetical membrane lipoprotein. | Preprotein translocase; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.991 |
UU489 | secG | UU489 | UU056 | Unique hypothetical membrane lipoprotein. | Unique hypothetical; Involved in protein export. Participates in an early event of protein translocation (By similarity); Belongs to the SecG family. | 0.999 |
UU489 | secY | UU489 | UU250 | Unique hypothetical membrane lipoprotein. | Preprotein translocase; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.999 |
UU580 | UU489 | UU580 | UU489 | Unique hypothetical; Belongs to the SecE/SEC61-gamma family. | Unique hypothetical membrane lipoprotein. | 0.999 |
UU580 | rpL15 | UU580 | UU249 | Unique hypothetical; Belongs to the SecE/SEC61-gamma family. | Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.955 |
UU580 | rpL18 | UU580 | UU247 | Unique hypothetical; Belongs to the SecE/SEC61-gamma family. | Ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. | 0.929 |
UU580 | rpL24 | UU580 | UU242 | Unique hypothetical; Belongs to the SecE/SEC61-gamma family. | Ribosomal protein L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.914 |
UU580 | rpL3 | UU580 | UU231 | Unique hypothetical; Belongs to the SecE/SEC61-gamma family. | Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 0.949 |
UU580 | rpL4 | UU580 | UU232 | Unique hypothetical; Belongs to the SecE/SEC61-gamma family. | Ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | 0.947 |
UU580 | rpL6 | UU580 | UU246 | Unique hypothetical; Belongs to the SecE/SEC61-gamma family. | Ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. | 0.940 |
UU580 | secA | UU580 | UU119 | Unique hypothetical; Belongs to the SecE/SEC61-gamma family. | Preprotein translocase; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.997 |
UU580 | secG | UU580 | UU056 | Unique hypothetical; Belongs to the SecE/SEC61-gamma family. | Unique hypothetical; Involved in protein export. Participates in an early event of protein translocation (By similarity); Belongs to the SecG family. | 0.999 |
UU580 | secY | UU580 | UU250 | Unique hypothetical; Belongs to the SecE/SEC61-gamma family. | Preprotein translocase; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.999 |
rpL15 | UU580 | UU249 | UU580 | Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | Unique hypothetical; Belongs to the SecE/SEC61-gamma family. | 0.955 |
rpL15 | rpL18 | UU249 | UU247 | Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | Ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. | 0.999 |
rpL15 | rpL24 | UU249 | UU242 | Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | Ribosomal protein L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.999 |
rpL15 | rpL3 | UU249 | UU231 | Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 0.999 |
rpL15 | rpL4 | UU249 | UU232 | Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | Ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | 0.999 |
rpL15 | rpL6 | UU249 | UU246 | Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | Ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. | 0.999 |