STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GLMSGLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE ISOMERIZING; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (595 aa)    
Predicted Functional Partners:
glmM
PUTATIVE PHOSPHO-SUGAR MUTASE; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
 
 
 0.958
WS1202
GLUTAMATE SYNTHASE, LARGE SUBUNIT.
   
 0.951
CARB
CARBAMOYL-PHOSPHATE SYNTHASE LARGE CHAIN; Belongs to the CarB family.
   
 0.940
pgi
GLUCOSE-6-PHOSPHATE ISOMERASE; Belongs to the GPI family.
  
 
 0.934
GLNA
GLUTAMINE SYNTHETASE.
  
 
 0.922
glmU
UDP-N-ACETYLGLUCOSAMINE PYROPHOSPHORYLASE GLMU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family.
  
 0.921
PURF
AMIDOPHOSPHORIBOSYLTRANSFERASE; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
 
  
0.918
purQ
GLYCINAMIDINE SYNTHETASE; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of th [...]
    
 0.914
gltD
GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN GLUTAMATESYNTHASE BETA SUBUNIT NADPH-GOGAT GLTS BETA CHAIN.
    
 0.912
CARA
CARBAMOYL-PHOSPHATE SYNTHASE SMALL CHAIN; Belongs to the CarA family.
    
 0.911
Your Current Organism:
Wolinella succinogenes
NCBI taxonomy Id: 273121
Other names: W. succinogenes DSM 1740, Wolinella succinogenes DSM 1740
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