STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
WS0366Hypothetical protein. (149 aa)    
Predicted Functional Partners:
gyrA
DNA GYRASE SUBUNIT A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
       0.816
WS0367
SIGNAL-TRANSDUCTION REGULATORY PROTEIN.
       0.782
asd
ASPARTATE-B-SEMIALDEHYDE DEHYDROGENASE; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
       0.782
WS0369
PUTATIVE INTEGRAL MEMBRANE PROTEIN.
       0.749
HEME
UROPORPHYRINOGEN DECARBOXYLASE; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
       0.690
WS0371
Conserved hypothetical protein.
       0.676
WS0372
Conserved hypothetical protein.
       0.676
WS0374
Conserved hypothetical protein.
       0.631
WS0373
EXTRACELLULAR SOLUTE-BINDING PROTEIN, PUTATIVE; Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
       0.615
WS0364
Hypothetical protein.
       0.603
Your Current Organism:
Wolinella succinogenes
NCBI taxonomy Id: 273121
Other names: W. succinogenes DSM 1740, Wolinella succinogenes DSM 1740
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.