node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
APT | GUAB | WS1350 | WS1895 | ADENINE PHOSPHORIBOSYLTRANSFERASE; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.596 |
APT | RIBD | WS1350 | WS2019 | ADENINE PHOSPHORIBOSYLTRANSFERASE; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | PUTATIVE RIBOFLAVIN-SPECIFIC DEAMINASE EC 3.5.4. | 0.501 |
APT | WS0502 | WS1350 | WS0502 | ADENINE PHOSPHORIBOSYLTRANSFERASE; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | TRANSLATION INITIATION INHIBITOR. | 0.902 |
EFG | RPMA | WS0470 | WS0504 | ELONGATION FACTOR G (FRAGMENT); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 su [...] | 50S RIBOSOMAL PROTEIN L27; Belongs to the bacterial ribosomal protein bL27 family. | 0.975 |
EFG | WS0502 | WS0470 | WS0502 | ELONGATION FACTOR G (FRAGMENT); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 su [...] | TRANSLATION INITIATION INHIBITOR. | 0.853 |
EFG | rplU | WS0470 | WS0503 | ELONGATION FACTOR G (FRAGMENT); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 su [...] | RIBOSOMAL PROTEIN L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.982 |
FTSI | WS0502 | WS0500 | WS0502 | Hypothetical protein. | TRANSLATION INITIATION INHIBITOR. | 0.554 |
GUAB | APT | WS1895 | WS1350 | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | ADENINE PHOSPHORIBOSYLTRANSFERASE; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.596 |
GUAB | RIBD | WS1895 | WS2019 | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | PUTATIVE RIBOFLAVIN-SPECIFIC DEAMINASE EC 3.5.4. | 0.542 |
GUAB | WS0502 | WS1895 | WS0502 | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | TRANSLATION INITIATION INHIBITOR. | 0.477 |
RIBD | APT | WS2019 | WS1350 | PUTATIVE RIBOFLAVIN-SPECIFIC DEAMINASE EC 3.5.4. | ADENINE PHOSPHORIBOSYLTRANSFERASE; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.501 |
RIBD | GUAB | WS2019 | WS1895 | PUTATIVE RIBOFLAVIN-SPECIFIC DEAMINASE EC 3.5.4. | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.542 |
RIBD | WS0502 | WS2019 | WS0502 | PUTATIVE RIBOFLAVIN-SPECIFIC DEAMINASE EC 3.5.4. | TRANSLATION INITIATION INHIBITOR. | 0.473 |
RIBD | ilvC | WS2019 | WS1878 | PUTATIVE RIBOFLAVIN-SPECIFIC DEAMINASE EC 3.5.4. | Ketol-acid reductoisomerase (NADP(+)); Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.622 |
RPMA | EFG | WS0504 | WS0470 | 50S RIBOSOMAL PROTEIN L27; Belongs to the bacterial ribosomal protein bL27 family. | ELONGATION FACTOR G (FRAGMENT); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 su [...] | 0.975 |
RPMA | WS0502 | WS0504 | WS0502 | 50S RIBOSOMAL PROTEIN L27; Belongs to the bacterial ribosomal protein bL27 family. | TRANSLATION INITIATION INHIBITOR. | 0.600 |
RPMA | rplU | WS0504 | WS0503 | 50S RIBOSOMAL PROTEIN L27; Belongs to the bacterial ribosomal protein bL27 family. | RIBOSOMAL PROTEIN L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.998 |
WS0502 | APT | WS0502 | WS1350 | TRANSLATION INITIATION INHIBITOR. | ADENINE PHOSPHORIBOSYLTRANSFERASE; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.902 |
WS0502 | EFG | WS0502 | WS0470 | TRANSLATION INITIATION INHIBITOR. | ELONGATION FACTOR G (FRAGMENT); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 su [...] | 0.853 |
WS0502 | FTSI | WS0502 | WS0500 | TRANSLATION INITIATION INHIBITOR. | Hypothetical protein. | 0.554 |