node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ILVD | ILVH | WS0130 | WS0102 | DIHYDROXY-ACID DEHYDRATASE; Belongs to the IlvD/Edd family. | ACETOLACTATE SYNTHASE SMALL SUBUNIT. | 0.913 |
ILVD | LEUA | WS0130 | WS0624 | DIHYDROXY-ACID DEHYDRATASE; Belongs to the IlvD/Edd family. | 2-ISOPROPYLMALATE SYNTHASE; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.976 |
ILVD | LEUD-1 | WS0130 | WS1812 | DIHYDROXY-ACID DEHYDRATASE; Belongs to the IlvD/Edd family. | 3-ISOPROPYLMALATE DEHYDRATASE, SMALL SUBUNIT LEUD-1; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. | 0.850 |
ILVD | NIFV1 | WS0130 | WS1396 | DIHYDROXY-ACID DEHYDRATASE; Belongs to the IlvD/Edd family. | HOMOCITRATE SYTHASE 1; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.794 |
ILVD | WS1579 | WS0130 | WS1579 | DIHYDROXY-ACID DEHYDRATASE; Belongs to the IlvD/Edd family. | Hypothetical protein. | 0.900 |
ILVD | ilvC | WS0130 | WS1878 | DIHYDROXY-ACID DEHYDRATASE; Belongs to the IlvD/Edd family. | Ketol-acid reductoisomerase (NADP(+)); Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.995 |
ILVD | leuB | WS0130 | WS1813 | DIHYDROXY-ACID DEHYDRATASE; Belongs to the IlvD/Edd family. | ISOPROPYLMALATE DEHYDROGENASE; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily. | 0.909 |
ILVD | leuC | WS0130 | WS0559 | DIHYDROXY-ACID DEHYDRATASE; Belongs to the IlvD/Edd family. | 3-ISOPROPYLMALATE DEHYDRATASE, LARGE SUBUNIT; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.909 |
ILVH | ILVD | WS0102 | WS0130 | ACETOLACTATE SYNTHASE SMALL SUBUNIT. | DIHYDROXY-ACID DEHYDRATASE; Belongs to the IlvD/Edd family. | 0.913 |
ILVH | LEUA | WS0102 | WS0624 | ACETOLACTATE SYNTHASE SMALL SUBUNIT. | 2-ISOPROPYLMALATE SYNTHASE; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.932 |
ILVH | LEUD-1 | WS0102 | WS1812 | ACETOLACTATE SYNTHASE SMALL SUBUNIT. | 3-ISOPROPYLMALATE DEHYDRATASE, SMALL SUBUNIT LEUD-1; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. | 0.873 |
ILVH | NIFV1 | WS0102 | WS1396 | ACETOLACTATE SYNTHASE SMALL SUBUNIT. | HOMOCITRATE SYTHASE 1; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.677 |
ILVH | WS0171 | WS0102 | WS0171 | ACETOLACTATE SYNTHASE SMALL SUBUNIT. | MALIC ENZYME. | 0.823 |
ILVH | WS0565 | WS0102 | WS0565 | ACETOLACTATE SYNTHASE SMALL SUBUNIT. | PROBABLE TRANSCARBOXYLASE SUBUNIT. | 0.801 |
ILVH | WS1579 | WS0102 | WS1579 | ACETOLACTATE SYNTHASE SMALL SUBUNIT. | Hypothetical protein. | 0.800 |
ILVH | ilvC | WS0102 | WS1878 | ACETOLACTATE SYNTHASE SMALL SUBUNIT. | Ketol-acid reductoisomerase (NADP(+)); Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.996 |
ILVH | leuB | WS0102 | WS1813 | ACETOLACTATE SYNTHASE SMALL SUBUNIT. | ISOPROPYLMALATE DEHYDROGENASE; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily. | 0.987 |
ILVH | leuC | WS0102 | WS0559 | ACETOLACTATE SYNTHASE SMALL SUBUNIT. | 3-ISOPROPYLMALATE DEHYDRATASE, LARGE SUBUNIT; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.873 |
LEUA | ILVD | WS0624 | WS0130 | 2-ISOPROPYLMALATE SYNTHASE; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | DIHYDROXY-ACID DEHYDRATASE; Belongs to the IlvD/Edd family. | 0.976 |
LEUA | ILVH | WS0624 | WS0102 | 2-ISOPROPYLMALATE SYNTHASE; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | ACETOLACTATE SYNTHASE SMALL SUBUNIT. | 0.932 |