node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
APT | GUAA | WS1350 | WS1603 | ADENINE PHOSPHORIBOSYLTRANSFERASE; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GMP SYNTHASE; Catalyzes the synthesis of GMP from XMP. | 0.993 |
APT | GUAB | WS1350 | WS1895 | ADENINE PHOSPHORIBOSYLTRANSFERASE; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.596 |
APT | SURE | WS1350 | WS1678 | ADENINE PHOSPHORIBOSYLTRANSFERASE; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | SURVIVAL PROTEIN SURE-Predicted acid phosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.914 |
APT | WS2175 | WS1350 | WS2175 | ADENINE PHOSPHORIBOSYLTRANSFERASE; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | PUTATIVE NUCLEOTIDE PHOSPHORIBOSYLTRANSFERASE. | 0.922 |
APT | gmk | WS1350 | WS0188 | ADENINE PHOSPHORIBOSYLTRANSFERASE; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GUANYLATE KINASE; Essential for recycling GMP and indirectly, cGMP. | 0.953 |
APT | ppnP | WS1350 | WS0164 | ADENINE PHOSPHORIBOSYLTRANSFERASE; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Conserved hypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. | 0.900 |
FLIE | WS2175 | WS1664 | WS2175 | FLAGELLAR HOOK-BASAL BODY PROTEIN. | PUTATIVE NUCLEOTIDE PHOSPHORIBOSYLTRANSFERASE. | 0.562 |
GUAA | APT | WS1603 | WS1350 | GMP SYNTHASE; Catalyzes the synthesis of GMP from XMP. | ADENINE PHOSPHORIBOSYLTRANSFERASE; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.993 |
GUAA | GUAB | WS1603 | WS1895 | GMP SYNTHASE; Catalyzes the synthesis of GMP from XMP. | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.997 |
GUAA | SURE | WS1603 | WS1678 | GMP SYNTHASE; Catalyzes the synthesis of GMP from XMP. | SURVIVAL PROTEIN SURE-Predicted acid phosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.948 |
GUAA | WS1795 | WS1603 | WS1795 | GMP SYNTHASE; Catalyzes the synthesis of GMP from XMP. | Conserved hypothetical protein-Xanthosine triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.969 |
GUAA | WS2175 | WS1603 | WS2175 | GMP SYNTHASE; Catalyzes the synthesis of GMP from XMP. | PUTATIVE NUCLEOTIDE PHOSPHORIBOSYLTRANSFERASE. | 0.910 |
GUAA | WS2176 | WS1603 | WS2176 | GMP SYNTHASE; Catalyzes the synthesis of GMP from XMP. | Conserved hypothetical protein. | 0.504 |
GUAA | gmk | WS1603 | WS0188 | GMP SYNTHASE; Catalyzes the synthesis of GMP from XMP. | GUANYLATE KINASE; Essential for recycling GMP and indirectly, cGMP. | 0.961 |
GUAB | APT | WS1895 | WS1350 | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | ADENINE PHOSPHORIBOSYLTRANSFERASE; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.596 |
GUAB | GUAA | WS1895 | WS1603 | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | GMP SYNTHASE; Catalyzes the synthesis of GMP from XMP. | 0.997 |
GUAB | SURE | WS1895 | WS1678 | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | SURVIVAL PROTEIN SURE-Predicted acid phosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.947 |
GUAB | WS1795 | WS1895 | WS1795 | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Conserved hypothetical protein-Xanthosine triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.949 |
GUAB | WS2175 | WS1895 | WS2175 | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | PUTATIVE NUCLEOTIDE PHOSPHORIBOSYLTRANSFERASE. | 0.946 |
GUAB | WS2176 | WS1895 | WS2176 | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Conserved hypothetical protein. | 0.518 |