WS2213 protein (Wolinella succinogenes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

WS2213

SIGMA-54 INTERACTING PROTEIN. (507 aa)

Predicted Functional Partners:

DEF

0.942

WS1883

0.880

WS2211

0.800

CLPP

0.760

TIG

0.752

RUVC

0.610

FLII

0.579

WS1801

0.573

WS0850

0.507

WS0614

0.464

Your Current Organism:

Wolinella succinogenes

NCBI taxonomy Id: 273121
Other names: W. succinogenes DSM 1740, Wolinella succinogenes DSM 1740

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CLPP	DEF	WS2210	WS2212	ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.	POLYPEPTIDE DEFORMYLASE PDF FORMYLMETHIONINEDEFORMYLASE; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	0.909
CLPP	FLII	WS2210	WS2207	ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.	FLAGELLUM-SPECIFIC ATP SYNTHASE.	0.610
CLPP	TIG	WS2210	WS2209	ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.	PUTATIVE TRIGGER FACTOR PROTEIN; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.	0.939
CLPP	WS0850	WS2210	WS0850	ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.	SENSORY TRANSDUCTION HISTIDINE KINASE.	0.477
CLPP	WS2211	WS2210	WS2211	ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.	Hypothetical protein.	0.772
CLPP	WS2213	WS2210	WS2213	ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.	SIGMA-54 INTERACTING PROTEIN.	0.760
DEF	CLPP	WS2212	WS2210	POLYPEPTIDE DEFORMYLASE PDF FORMYLMETHIONINEDEFORMYLASE; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.	0.909
DEF	FLII	WS2212	WS2207	POLYPEPTIDE DEFORMYLASE PDF FORMYLMETHIONINEDEFORMYLASE; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	FLAGELLUM-SPECIFIC ATP SYNTHASE.	0.571
DEF	RUVC	WS2212	WS2229	POLYPEPTIDE DEFORMYLASE PDF FORMYLMETHIONINEDEFORMYLASE; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	CROSSOVER JUNCTION ENDODEOXYRIBONUCLEASE; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.	0.408
DEF	TIG	WS2212	WS2209	POLYPEPTIDE DEFORMYLASE PDF FORMYLMETHIONINEDEFORMYLASE; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	PUTATIVE TRIGGER FACTOR PROTEIN; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.	0.962
DEF	WS2211	WS2212	WS2211	POLYPEPTIDE DEFORMYLASE PDF FORMYLMETHIONINEDEFORMYLASE; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	Hypothetical protein.	0.794
DEF	WS2213	WS2212	WS2213	POLYPEPTIDE DEFORMYLASE PDF FORMYLMETHIONINEDEFORMYLASE; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	SIGMA-54 INTERACTING PROTEIN.	0.942
FLII	CLPP	WS2207	WS2210	FLAGELLUM-SPECIFIC ATP SYNTHASE.	ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.	0.610
FLII	DEF	WS2207	WS2212	FLAGELLUM-SPECIFIC ATP SYNTHASE.	POLYPEPTIDE DEFORMYLASE PDF FORMYLMETHIONINEDEFORMYLASE; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	0.571
FLII	TIG	WS2207	WS2209	FLAGELLUM-SPECIFIC ATP SYNTHASE.	PUTATIVE TRIGGER FACTOR PROTEIN; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.	0.610
FLII	WS0850	WS2207	WS0850	FLAGELLUM-SPECIFIC ATP SYNTHASE.	SENSORY TRANSDUCTION HISTIDINE KINASE.	0.677
FLII	WS1801	WS2207	WS1801	FLAGELLUM-SPECIFIC ATP SYNTHASE.	FLAGELLAR BASAL-BODY ROD PROTEIN FLGG.	0.895
FLII	WS2211	WS2207	WS2211	FLAGELLUM-SPECIFIC ATP SYNTHASE.	Hypothetical protein.	0.678
FLII	WS2213	WS2207	WS2213	FLAGELLUM-SPECIFIC ATP SYNTHASE.	SIGMA-54 INTERACTING PROTEIN.	0.579
RUVC	DEF	WS2229	WS2212	CROSSOVER JUNCTION ENDODEOXYRIBONUCLEASE; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.	POLYPEPTIDE DEFORMYLASE PDF FORMYLMETHIONINEDEFORMYLASE; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	0.408