STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PEX2_066590Zinc/iron permease, fungal/plant. (351 aa)    
Predicted Functional Partners:
MMM1
Maintenance of mitochondrial morphology protein 1; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta- barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 su [...]
    
 0.767
PEX2_040460
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
    
 0.664
MDM34
Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.
    
 0.664
PEX2_052520
Bacterial surface antigen (D15).
    
 
 0.647
PEX2_037340
Mitochondrial outer membrane transport complex, Tom37/metaxin.
    
 
 0.608
PEX2_060900
Mitochondrial outer membrane transport complex, Tom37/metaxin.
    
 
 0.608
PEX2_047030
Zinc/iron permease.
   
 
 0.590
PEX2_089670
HRXXH domain-containing protein.
   
 
 0.527
PEX2_052790
Major facilitator superfamily domain, general substrate transporter.
      
 0.519
PEX2_021710
Zinc/iron permease.
    
 
 0.510
Your Current Organism:
Penicillium expansum
NCBI taxonomy Id: 27334
Other names: ATCC 7861, CBS 325.48, P. expansum
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.