STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PEX2_074590Zinc finger, MYND-type. (225 aa)    
Predicted Functional Partners:
PEX2_044840
Uncharacterized protein.
    
 0.766
PEX2_000360
Histone-binding protein RBBP4.
    
 0.759
PEX2_005640
WD_REPEATS_REGION domain-containing protein.
    
 0.748
PEX2_051690
Concanavalin A-like lectin/glucanases superfamily.
    
 0.745
PEX2_037470
Histone H2B; Belongs to the histone H2B family.
    
 0.714
PEX2_006720
Ubiquitin supergroup.
    
  0.699
PEX2_012120
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.695
PEX2_003060
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.695
PEX2_087010
Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones.
    
 0.691
PEX2_060260
Transcription factor jumonji, JmjN.
   
 0.687
Your Current Organism:
Penicillium expansum
NCBI taxonomy Id: 27334
Other names: ATCC 7861, CBS 325.48, P. expansum
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.