STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PEX2_016720GPI biosynthesis protein Pig-F. (287 aa)    
Predicted Functional Partners:
PEX2_039390
GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.
   
 
 0.946
PEX2_106100
Mannosyltransferase.
   
 
 0.942
PEX2_092640
Gpi16 subunit, GPI transamidase component.
     
 0.942
KAE1
tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. Th [...]
    
 0.941
PEX2_104630
Pyridoxal phosphate-dependent transferase, major region, subdomain 1.
     
 0.938
PEX2_028520
Pyridoxal phosphate-dependent transferase, major region, subdomain 2.
     
 0.938
PEX2_057910
Sphingolipid delta4-desaturase, N-terminal.
   
 
 0.910
PEX2_043130
Fatty acid hydroxylase; Belongs to the sterol desaturase family.
    
 0.909
PEX2_033120
Phosphatidic acid phosphatase type 2/haloperoxidase.
    
 0.909
PEX2_090070
Neutral ceramidase.
     
 0.904
Your Current Organism:
Penicillium expansum
NCBI taxonomy Id: 27334
Other names: ATCC 7861, CBS 325.48, P. expansum
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