STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PEX2_028780Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha. (199 aa)    
Predicted Functional Partners:
PEX2_093840
Citrate synthase; Belongs to the citrate synthase family.
  
 0.901
PEX2_022590
Citrate synthase; Belongs to the citrate synthase family.
  
 0.901
PEX2_068350
Citrate synthase-like, core.
  
 0.901
PEX2_075870
Peptidase C48, SUMO/Sentrin/Ubl1.
  
 
 0.896
PEX2_047610
Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
  
 0.850
PEX2_086210
Uncharacterized protein.
  
 0.850
PEX2_019390
Uncharacterized protein.
  
 0.850
PEX2_086200
Uncharacterized protein.
  
 0.850
PEX2_051330
Isocitrate dehydrogenase [NAD] subunit, mitochondrial.
  
 0.832
PEX2_044910
Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 0.828
Your Current Organism:
Penicillium expansum
NCBI taxonomy Id: 27334
Other names: ATCC 7861, CBS 325.48, P. expansum
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.