STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PEX2_109860Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (270 aa)    
Predicted Functional Partners:
PEX2_019530
Uncharacterized protein.
   
 0.998
PEX2_002550
DNA-repair protein, UmuC-like, N-terminal.
   
 0.998
PEX2_015670
3'-5' exonuclease domain-containing protein.
  
 0.998
PEX2_020270
Sec20.
  
 0.994
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
   
 0.992
PEX2_021530
DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal.
  
 0.989
PEX2_062550
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
   
 0.985
PEX2_073920
DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal.
  
 0.985
PEX2_047250
DNA ligase.
   
 0.983
PEX2_041630
DNA polymerase.
  
 0.981
Your Current Organism:
Penicillium expansum
NCBI taxonomy Id: 27334
Other names: ATCC 7861, CBS 325.48, P. expansum
Server load: low (26%) [HD]