STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PEX2_054120AMP-dependent synthetase/ligase. (689 aa)    
Predicted Functional Partners:
PEX2_084500
Thiolase-like, subgroup; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.915
PEX2_021370
Pyruvate carboxyltransferase.
 
 
 0.903
PEX2_104110
Dehydrogenase, multihelical.
   
 
 0.900
PEX2_034960
Dehydrogenase, multihelical.
   
 
 0.900
PEX2_035560
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
   
 
 0.894
PEX2_067440
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
   
 
 0.894
PEX2_104910
Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
  
 
 0.886
PEX2_051740
Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
  
 
 0.886
PEX2_028530
Uncharacterized protein.
  
  
 
0.878
PEX2_054560
Transcription factor IIIC, putative zinc-finger.
  
 
 0.855
Your Current Organism:
Penicillium expansum
NCBI taxonomy Id: 27334
Other names: ATCC 7861, CBS 325.48, P. expansum
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