node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PEX2_003060 | PEX2_005640 | A0A0A2JNE5 | A0A0A2IAI8 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | WD_REPEATS_REGION domain-containing protein. | 0.960 |
PEX2_003060 | PEX2_012130 | A0A0A2JNE5 | A0A0A2I765 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Histone H3; Belongs to the histone H3 family. | 0.995 |
PEX2_003060 | PEX2_026180 | A0A0A2JNE5 | A0A0A2KEU8 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Histone-fold. | 0.974 |
PEX2_003060 | PEX2_029190 | A0A0A2JNE5 | A0A0A2JJV4 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Cleavage/polyadenylation specificity factor, A subunit, C-terminal. | 0.598 |
PEX2_003060 | PEX2_034600 | A0A0A2JNE5 | A0A0A2JEX5 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Uncharacterized protein. | 0.724 |
PEX2_003060 | PEX2_051460 | A0A0A2JNE5 | A0A0A2I9Q7 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation. | 0.944 |
PEX2_003060 | PEX2_051690 | A0A0A2JNE5 | A0A0A2IV45 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Concanavalin A-like lectin/glucanases superfamily. | 0.941 |
PEX2_005640 | PEX2_003060 | A0A0A2IAI8 | A0A0A2JNE5 | WD_REPEATS_REGION domain-containing protein. | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.960 |
PEX2_005640 | PEX2_012120 | A0A0A2IAI8 | A0A0A2I954 | WD_REPEATS_REGION domain-containing protein. | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.960 |
PEX2_005640 | PEX2_012130 | A0A0A2IAI8 | A0A0A2I765 | WD_REPEATS_REGION domain-containing protein. | Histone H3; Belongs to the histone H3 family. | 0.966 |
PEX2_005640 | PEX2_026180 | A0A0A2IAI8 | A0A0A2KEU8 | WD_REPEATS_REGION domain-containing protein. | Histone-fold. | 0.966 |
PEX2_005640 | PEX2_029190 | A0A0A2IAI8 | A0A0A2JJV4 | WD_REPEATS_REGION domain-containing protein. | Cleavage/polyadenylation specificity factor, A subunit, C-terminal. | 0.749 |
PEX2_005640 | PEX2_034600 | A0A0A2IAI8 | A0A0A2JEX5 | WD_REPEATS_REGION domain-containing protein. | Uncharacterized protein. | 0.896 |
PEX2_005640 | PEX2_051460 | A0A0A2IAI8 | A0A0A2I9Q7 | WD_REPEATS_REGION domain-containing protein. | Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation. | 0.997 |
PEX2_005640 | PEX2_051690 | A0A0A2IAI8 | A0A0A2IV45 | WD_REPEATS_REGION domain-containing protein. | Concanavalin A-like lectin/glucanases superfamily. | 0.999 |
PEX2_012120 | PEX2_005640 | A0A0A2I954 | A0A0A2IAI8 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | WD_REPEATS_REGION domain-containing protein. | 0.960 |
PEX2_012120 | PEX2_012130 | A0A0A2I954 | A0A0A2I765 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Histone H3; Belongs to the histone H3 family. | 0.999 |
PEX2_012120 | PEX2_026180 | A0A0A2I954 | A0A0A2KEU8 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Histone-fold. | 0.974 |
PEX2_012120 | PEX2_029190 | A0A0A2I954 | A0A0A2JJV4 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Cleavage/polyadenylation specificity factor, A subunit, C-terminal. | 0.598 |
PEX2_012120 | PEX2_034600 | A0A0A2I954 | A0A0A2JEX5 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Uncharacterized protein. | 0.724 |