PEX2_090180 protein (Penicillium expansum) - STRING interaction network

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Predicted Interactions

gene neighborhood

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textmining

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Score

PEX2_090180

Tetratricopeptide-like helical. (352 aa)

Predicted Functional Partners:

PEX2_073940

0.959

PEX2_102390

0.953

GET3

0.912

PEX2_109810

0.866

PEX2_060050

0.807

PEX2_020960

0.805

PEX2_081290

0.805

PEX2_030610

0.783

PEX2_086530

0.768

PEX2_005070

0.762

Your Current Organism:

Penicillium expansum

NCBI taxonomy Id: 27334
Other names: ATCC 7861, CBS 325.48, P. expansum

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GET3	PEX2_030610	A0A0A2I631	A0A0A2J1C6	ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]	Syntaxin, N-terminal.	0.828
GET3	PEX2_073940	A0A0A2I631	A0A0A2KUD6	ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]	Uncharacterized protein family UPF0363.	0.991
GET3	PEX2_086530	A0A0A2I631	A0A0A2I8X2	ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]	ATPase, AAA-type, core; Belongs to the ClpA/ClpB family.	0.439
GET3	PEX2_090180	A0A0A2I631	A0A0A2JRA5	ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]	Tetratricopeptide-like helical.	0.912
GET3	PEX2_102390	A0A0A2I631	A0A0A2LAC5	ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]	Ubiquitin supergroup.	0.971
GET3	PEX2_109810	A0A0A2I631	A0A0A2IR44	ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.	0.856
PEX2_005070	PEX2_090180	A0A0A2JK21	A0A0A2JRA5	DOC domain-containing protein.	Tetratricopeptide-like helical.	0.762
PEX2_005070	PEX2_102390	A0A0A2JK21	A0A0A2LAC5	DOC domain-containing protein.	Ubiquitin supergroup.	0.719
PEX2_020960	PEX2_060050	A0A0A2K0K3	A0A0A2JFE5	FMN-binding split barrel-like protein.	Heat shock protein 70 family.	0.939
PEX2_020960	PEX2_086530	A0A0A2K0K3	A0A0A2I8X2	FMN-binding split barrel-like protein.	ATPase, AAA-type, core; Belongs to the ClpA/ClpB family.	0.836
PEX2_020960	PEX2_090180	A0A0A2K0K3	A0A0A2JRA5	FMN-binding split barrel-like protein.	Tetratricopeptide-like helical.	0.805
PEX2_020960	PEX2_102390	A0A0A2K0K3	A0A0A2LAC5	FMN-binding split barrel-like protein.	Ubiquitin supergroup.	0.649
PEX2_030610	GET3	A0A0A2J1C6	A0A0A2I631	Syntaxin, N-terminal.	ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]	0.828
PEX2_030610	PEX2_090180	A0A0A2J1C6	A0A0A2JRA5	Syntaxin, N-terminal.	Tetratricopeptide-like helical.	0.783
PEX2_030610	PEX2_109810	A0A0A2J1C6	A0A0A2IR44	Syntaxin, N-terminal.	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.	0.748
PEX2_060050	PEX2_020960	A0A0A2JFE5	A0A0A2K0K3	Heat shock protein 70 family.	FMN-binding split barrel-like protein.	0.939
PEX2_060050	PEX2_081290	A0A0A2JFE5	A0A0A2KA97	Heat shock protein 70 family.	Heat shock protein Hsp90, N-terminal.	0.939
PEX2_060050	PEX2_086530	A0A0A2JFE5	A0A0A2I8X2	Heat shock protein 70 family.	ATPase, AAA-type, core; Belongs to the ClpA/ClpB family.	0.890
PEX2_060050	PEX2_090180	A0A0A2JFE5	A0A0A2JRA5	Heat shock protein 70 family.	Tetratricopeptide-like helical.	0.807
PEX2_060050	PEX2_102390	A0A0A2JFE5	A0A0A2LAC5	Heat shock protein 70 family.	Ubiquitin supergroup.	0.584