STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PEX2_064360Pyruvate/Phosphoenolpyruvate kinase. (261 aa)    
Predicted Functional Partners:
PEX2_022530
Malate synthase; Belongs to the malate synthase family.
   
 
 0.793
PEX2_093840
Citrate synthase; Belongs to the citrate synthase family.
  
 0.771
PEX2_022590
Citrate synthase; Belongs to the citrate synthase family.
  
 0.771
PEX2_068350
Citrate synthase-like, core.
  
 0.771
PEX2_075380
Pyridoxal phosphate-dependent transferase, major region, subdomain 2.
  
 
 0.740
PEX2_001410
Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3.
    
 0.667
PEX2_043970
Succinate dehydrogenase, cytochrome b560 subunit.
    
 0.643
PEX2_044910
Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
    
 0.635
PEX2_107270
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
    
  0.628
PEX2_101950
Malate dehydrogenase.
  
 0.626
Your Current Organism:
Penicillium expansum
NCBI taxonomy Id: 27334
Other names: ATCC 7861, CBS 325.48, P. expansum
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.