STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PEX2_022590Citrate synthase; Belongs to the citrate synthase family. (465 aa)    
Predicted Functional Partners:
PEX2_101950
Malate dehydrogenase.
  
 0.990
PEX2_074190
Malate dehydrogenase, type 1; Belongs to the LDH/MDH superfamily.
  
 0.990
PEX2_053210
Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family.
  
 0.989
PEX2_029570
ATP-grasp fold, succinyl-CoA synthetase-type.
  
 0.988
PEX2_029580
Citrate synthase-like, core.
  
 0.988
PEX2_101920
Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 0.977
PEX2_034610
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
  
 0.970
PEX2_022530
Malate synthase; Belongs to the malate synthase family.
   
 0.966
PEX2_107270
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
  
 0.959
PEX2_007980
Acetyl-coenzyme A synthetase.
  
 0.958
Your Current Organism:
Penicillium expansum
NCBI taxonomy Id: 27334
Other names: ATCC 7861, CBS 325.48, P. expansum
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