node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PEX2_008270 | PEX2_011250 | A0A0A2JHD4 | A0A0A2I3C3 | 3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal. | Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids. | 0.976 |
PEX2_008270 | PEX2_026680 | A0A0A2JHD4 | A0A0A2KZY2 | 3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal. | Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. | 0.874 |
PEX2_008270 | PEX2_031400 | A0A0A2JHD4 | A0A0A2J210 | 3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal. | Fatty acid/sphingolipid desaturase. | 0.653 |
PEX2_008270 | PEX2_039870 | A0A0A2JHD4 | A0A0A2I8P6 | 3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal. | Ceramide very long chain fatty acid hydroxylase; Ceramide hydroxylase involved in the hydroxylation of sphingolipid-associated very long chain fatty acids. Postulated to hydroxylate the very long chain fatty acid of dihydroceramides and phytoceramides at C-2; Belongs to the sterol desaturase family. SCS7 subfamily. | 0.572 |
PEX2_008270 | PEX2_067250 | A0A0A2JHD4 | A0A0A2K1B9 | 3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal. | Fatty acid/sphingolipid desaturase. | 0.653 |
PEX2_008270 | PEX2_076820 | A0A0A2JHD4 | A0A0A2JN80 | 3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal. | Elongation of fatty acids protein. | 0.773 |
PEX2_008270 | PEX2_087800 | A0A0A2JHD4 | A0A0A2HY01 | 3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal. | Fatty acid/sphingolipid desaturase. | 0.653 |
PEX2_008270 | PEX2_102160 | A0A0A2JHD4 | A0A0A2IU83 | 3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal. | Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. | 0.907 |
PEX2_008270 | PEX2_102410 | A0A0A2JHD4 | A0A0A2K0F5 | 3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal. | Uncharacterized protein. | 0.805 |
PEX2_011250 | PEX2_008270 | A0A0A2I3C3 | A0A0A2JHD4 | Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids. | 3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal. | 0.976 |
PEX2_011250 | PEX2_026680 | A0A0A2I3C3 | A0A0A2KZY2 | Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids. | Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. | 0.888 |
PEX2_011250 | PEX2_031400 | A0A0A2I3C3 | A0A0A2J210 | Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids. | Fatty acid/sphingolipid desaturase. | 0.608 |
PEX2_011250 | PEX2_067250 | A0A0A2I3C3 | A0A0A2K1B9 | Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids. | Fatty acid/sphingolipid desaturase. | 0.608 |
PEX2_011250 | PEX2_076820 | A0A0A2I3C3 | A0A0A2JN80 | Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids. | Elongation of fatty acids protein. | 0.603 |
PEX2_011250 | PEX2_083580 | A0A0A2I3C3 | A0A0A2JBT2 | Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids. | Thiolase-like, subgroup; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | 0.583 |
PEX2_011250 | PEX2_087800 | A0A0A2I3C3 | A0A0A2HY01 | Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids. | Fatty acid/sphingolipid desaturase. | 0.608 |
PEX2_011250 | PEX2_102160 | A0A0A2I3C3 | A0A0A2IU83 | Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids. | Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. | 0.917 |
PEX2_011250 | PEX2_102410 | A0A0A2I3C3 | A0A0A2K0F5 | Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids. | Uncharacterized protein. | 0.611 |
PEX2_026680 | PEX2_008270 | A0A0A2KZY2 | A0A0A2JHD4 | Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. | 3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal. | 0.874 |
PEX2_026680 | PEX2_011250 | A0A0A2KZY2 | A0A0A2I3C3 | Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. | Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids. | 0.888 |