STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PEX2_105620Succinate dehydrogenase assembly factor 2, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer. (295 aa)    
Predicted Functional Partners:
PEX2_085950
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
  
 0.975
PEX2_105610
GOLD domain-containing protein.
 
      0.900
PEX2_105630
WD_REPEATS_REGION domain-containing protein.
 
      0.896
PEX2_066490
Flavocytochrome c.
  
 0.866
PEX2_028220
FAD_binding_2 domain-containing protein.
  
 0.866
PEX2_063550
FAD_binding_2 domain-containing protein.
  
 0.866
PEX2_099450
Uncharacterized protein.
  
 0.866
PEX2_003230
FAD_binding_2 domain-containing protein.
  
 0.866
PEX2_043970
Succinate dehydrogenase, cytochrome b560 subunit.
    
 0.834
PEX2_107270
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
  
 
 0.833
Your Current Organism:
Penicillium expansum
NCBI taxonomy Id: 27334
Other names: ATCC 7861, CBS 325.48, P. expansum
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.