A0A0H2RET9 protein (Schizopora paradoxa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

A0A0H2RET9

Fe2OG dioxygenase domain-containing protein. (291 aa)

Predicted Functional Partners:

A0A0H2R1M9

0.861

A0A0H2R1Q1

0.861

A0A0H2RC59

0.861

A0A0H2RD30

0.861

A0A0H2RH83

0.861

A0A0H2RNU7

0.861

A0A0H2S0I7

0.861

A0A0H2S1W0

0.861

A0A0H2S8M7

0.861

A0A0H2SC84

0.861

Your Current Organism:

Schizopora paradoxa

NCBI taxonomy Id: 27342
Other names: Hyphodontia paradoxa, S. paradoxa

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A0H2R1M9	A0A0H2RET9	Amino acid transporter.	Fe2OG dioxygenase domain-containing protein.	0.861
A0A0H2R1Q1	A0A0H2RET9	APC amino acid permease.	Fe2OG dioxygenase domain-containing protein.	0.861
A0A0H2RC59	A0A0H2RET9	Amino acid transporter.	Fe2OG dioxygenase domain-containing protein.	0.861
A0A0H2RD30	A0A0H2RET9	Amidase signature enzyme.	Fe2OG dioxygenase domain-containing protein.	0.861
A0A0H2RET9	A0A0H2R1M9	Fe2OG dioxygenase domain-containing protein.	Amino acid transporter.	0.861
A0A0H2RET9	A0A0H2R1Q1	Fe2OG dioxygenase domain-containing protein.	APC amino acid permease.	0.861
A0A0H2RET9	A0A0H2RC59	Fe2OG dioxygenase domain-containing protein.	Amino acid transporter.	0.861
A0A0H2RET9	A0A0H2RD30	Fe2OG dioxygenase domain-containing protein.	Amidase signature enzyme.	0.861
A0A0H2RET9	A0A0H2RH83	Fe2OG dioxygenase domain-containing protein.	Phospho-2-dehydro-3-deoxyheptonate aldolase; Belongs to the class-II DAHP synthase family.	0.861
A0A0H2RET9	A0A0H2RNU7	Fe2OG dioxygenase domain-containing protein.	L-methionine transporter.	0.861
A0A0H2RET9	A0A0H2S0I7	Fe2OG dioxygenase domain-containing protein.	Amino acid transporter.	0.861
A0A0H2RET9	A0A0H2S1W0	Fe2OG dioxygenase domain-containing protein.	Amidase signature enzyme.	0.861
A0A0H2RET9	A0A0H2S8M7	Fe2OG dioxygenase domain-containing protein.	General amidase.	0.861
A0A0H2RET9	A0A0H2SC84	Fe2OG dioxygenase domain-containing protein.	General amidase.	0.861
A0A0H2RH83	A0A0H2RET9	Phospho-2-dehydro-3-deoxyheptonate aldolase; Belongs to the class-II DAHP synthase family.	Fe2OG dioxygenase domain-containing protein.	0.861
A0A0H2RNU7	A0A0H2RET9	L-methionine transporter.	Fe2OG dioxygenase domain-containing protein.	0.861
A0A0H2S0I7	A0A0H2RET9	Amino acid transporter.	Fe2OG dioxygenase domain-containing protein.	0.861
A0A0H2S1W0	A0A0H2RET9	Amidase signature enzyme.	Fe2OG dioxygenase domain-containing protein.	0.861
A0A0H2S8M7	A0A0H2RET9	General amidase.	Fe2OG dioxygenase domain-containing protein.	0.861
A0A0H2SC84	A0A0H2RET9	General amidase.	Fe2OG dioxygenase domain-containing protein.	0.861

Network Stats

number of nodes:

11

number of edges:

49

average node degree:

8.91

avg. local clustering coefficient:

0.904

expected number of edges:

11

PPI enrichment p-value:

< 1.0e-16

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0008654

Phospholipid biosynthetic process

9 of 32

2.07

5.82

2.23e-15

GO:0008610

Lipid biosynthetic process

11 of 60

1.89

5.55

6.17e-18

GO:0044255

Cellular lipid metabolic process

11 of 76

1.78

4.87

3.38e-17

GO:0046474

Glycerophospholipid biosynthetic process

3 of 7

2.26

2.04

0.00012

GO:0008299

Isoprenoid biosynthetic process

3 of 10

2.1

1.88

0.00020

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0017169

CDP-alcohol phosphatidyltransferase activity

3 of 3

2.62

2.23

7.51e-05

GO:0008444

CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity

2 of 2

2.62

1.28

0.0046

GO:0016740

Transferase activity

10 of 633

0.82

0.79

1.81e-05

GO:0016772

Transferase activity, transferring phosphorus-containing groups

6 of 254

1.0

0.78

0.0027

GO:0003824

Catalytic activity

11 of 1975

0.37

0.29

0.0111

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:836

Glycerophospholipid metabolism, and Chromosome partition

7 of 18

2.21

4.93

1.84e-11

CL:847

Phosphate acyltransferases, and Acid phosphatase homologues

4 of 5

2.53

3.22

7.67e-07

CL:857

CDP-alcohol phosphatidyltransferase activity, and Zymogen

3 of 5

2.4

2.13

9.86e-05

CL:515

Mixed, incl. Isoprenoid biosynthetic process, and Ribosomal small subunit biogenesis

4 of 22

1.88

2.02

5.35e-05

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

amt00564

Glycerophospholipid metabolism

8 of 21

2.2

6.03

1.30e-14

amt00561

Glycerolipid metabolism

4 of 11

2.18

3.02

7.55e-07

amt00900

Terpenoid backbone biosynthesis

3 of 13

1.99

1.95

0.00011

amt01110

Biosynthesis of secondary metabolites

9 of 274

1.14

1.51

2.52e-08

amt01100

Metabolic pathways

9 of 638

0.77

0.73

1.98e-05

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0016020

Membrane

8 of 720

0.67

0.46

0.0111

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0594

Phospholipid biosynthesis

3 of 9

2.15

1.86

0.00024

KW-0808

Transferase

10 of 498

0.93

1.02

4.99e-07

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF01066

CDP-alcohol phosphatidyltransferase

3 of 4

2.5

1.95

0.00024

PF01255

Putative undecaprenyl diphosphate synthase

2 of 2

2.62

1.08

0.0108

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR043130

CDP-alcohol phosphatidyltransferase, transmembrane domain

3 of 4

2.5

1.73

0.00064

IPR000462

CDP-alcohol phosphatidyltransferase

3 of 4

2.5

1.73

0.00064

IPR036424

Decaprenyl diphosphate synthase-like superfamily

2 of 2

2.62

0.95

0.0188

IPR004570

CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

2 of 2

2.62

0.95

0.0188

IPR002123

Phospholipid/glycerol acyltransferase

2 of 2

2.62

0.95

0.0188

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00563

Phosphate acyltransferases

2 of 2

2.62

1.28

0.0046

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (22%) [HD]

Permalink

Credits

Access

Info

About

STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.

Network

Cooccurrence

Experiments

Neighborhood

Databases

Fusion

Textmining

Coexpression

© STRING Consortium 2024

Credits

Access

Info

About