STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VP01_92g12Uncharacterized protein. (193 aa)    
Predicted Functional Partners:
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP; Belongs to the cyclin family.
    
 0.867
VP01_664g11
Adenine phosphoribosyltransferase.
  
 0.866
VP01_350g2
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
  
 
 0.864
VP01_818g3
AMP deaminase.
  
 0.830
VP01_1837g2
Guanylate kinase.
   
 0.829
VP01_3403g2
Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
    
 0.808
VP01_1941g1
Uncharacterized protein.
  
 
 0.808
VP01_2367g3
Uncharacterized protein.
    
 0.804
VP01_1572g4
A_deaminase domain-containing protein.
  
 0.804
purH
Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase.
    
 0.791
Your Current Organism:
Puccinia sorghi
NCBI taxonomy Id: 27349
Other names: P. sorghi
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.