STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VP01_3353g1Ribonucleoside-diphosphate reductase small chain. (383 aa)    
Predicted Functional Partners:
VP01_2072g2
Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
 0.999
VP01_2736g6
Thymidylate kinase.
   
 
 0.941
VP01_2620g3
Nucleoside diphosphate kinase.
    
 0.935
ADK1
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.
     
 0.933
VP01_1837g2
Guanylate kinase.
   
 
 0.932
VP01_121g8
Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family.
    
  0.926
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
     
 0.925
VP01_3734g6
Uridylate kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP. Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.
     
 0.924
VP01_3188g3
Uncharacterized protein; Belongs to the adenylate kinase family.
     
 0.924
MCM7
DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]
   
  
 0.905
Your Current Organism:
Puccinia sorghi
NCBI taxonomy Id: 27349
Other names: P. sorghi
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