STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VP01_1625g12Uncharacterized protein. (693 aa)    
Predicted Functional Partners:
VP01_630g2
Protein kinase domain-containing protein.
    
 0.942
VP01_431g15
Protein kinase domain-containing protein.
    
 0.925
VP01_718g2
Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
    
 0.923
VP01_526g9
Uncharacterized protein.
    
 0.923
VP01_249g11
Uncharacterized protein.
   
 0.920
VP01_1709g4
3'-5' exonuclease domain-containing protein.
   
 0.920
VP01_1087g5
Uncharacterized protein.
   
 0.920
VP01_1197g2
Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
   
 0.913
VP01_198g2
Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability.
   
 0.907
VP01_3358g1
Uncharacterized protein.
    
 0.906
Your Current Organism:
Puccinia sorghi
NCBI taxonomy Id: 27349
Other names: P. sorghi
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.