STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VP01_1549g6Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. (580 aa)    
Predicted Functional Partners:
VP01_896g5
Dihydrofolate reductase; Belongs to the dihydrofolate reductase family.
     
 0.963
thyA
Thymidylate synthase.
     
 0.930
VP01_321g3
Flavoprotein domain-containing protein.
     
 0.899
folP
Dihydropteroate synthase.
  
 
 0.894
VP01_515g13
Uncharacterized protein.
  
 
 0.894
VP01_4655g2
Uncharacterized protein.
  
 
 0.894
VP01_826g6
FSH1 domain-containing protein.
     
 0.868
VP01_2145g1
Uncharacterized protein.
  
 
 0.853
VP01_1424g4
Dihydrofolate synthetase; Belongs to the folylpolyglutamate synthase family.
  
  
0.853
VP01_1179g2
FolB domain-containing protein.
  
 
 0.832
Your Current Organism:
Puccinia sorghi
NCBI taxonomy Id: 27349
Other names: P. sorghi
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