STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KAE1tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. Th [...] (369 aa)    
Predicted Functional Partners:
VP01_1878g6
Uncharacterized protein; Belongs to the CGI121/TPRKB family.
    
 0.996
VP01_1156g6
Protein kinase domain-containing protein.
  
 0.996
VP01_2812g4
Uncharacterized protein.
   
 0.992
VP01_62g19
YrdC-like domain-containing protein.
  
 
 0.882
coaE
Dephospho-CoA kinase.
    
 0.755
VP01_3028g4
Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.
 
      0.741
VP01_6099g1
Protein-tyrosine phosphatase.
    
  0.731
VP01_1699g3
Methylase.
    
 0.689
VP01_1167g3
Methyltranfer_dom domain-containing protein.
    
 0.689
VP01_1178g3
Uncharacterized protein.
 
    
 0.673
Your Current Organism:
Puccinia sorghi
NCBI taxonomy Id: 27349
Other names: P. sorghi
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