STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
endADNA-specific endonuclease I. (231 aa)    
Predicted Functional Partners:
nucA
Nuclease; Catalyzes the hydrolysis of both DNA and RNA, double- or single-stranded, at the 3'position of the phosphodiester bond to produce 5'-phosphorylated mono-, di-, tri- and tetranucleotides. DNA is a slightly better substrate than RNA.
     
 0.850
gst
Glutathione S-transferase; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles; Belongs to the GST superfamily. Beta family.
      
 0.659
yciS
Putative membrane protein; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family.
      
 0.657
argH
Argininosuccinate lyase.
      
 0.652
sprT
Putative metallopeptidase; Belongs to the SprT family.
     
 0.624
rsmE
Ribosomal RNA small subunit methyltransferase E; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.
       0.620
gshB
Glutathione synthetase; Belongs to the prokaryotic GSH synthase family.
       0.604
CDG13998.1
Hypothetical protein; Belongs to the UPF0301 (AlgH) family.
       0.423
yqgF
Putative holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.
       0.413
yciU
Hypothetical protein; Belongs to the UPF0263 family.
  
     0.408
Your Current Organism:
Serratia marcescens
NCBI taxonomy Id: 273526
Other names: S. marcescens subsp. marcescens Db11, Serratia marcescens subsp. marcescens Db11, Serratia marcescens subsp. marcescens str. Db11, Serratia marcescens subsp. marcescens strain Db11
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