node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Kgd | LipM | BW34_02337 | BW34_00813 | Oxoglutarate dehydrogenase (Succinyl-transferring), E1 component. | Lipoate-protein ligase A. | 0.899 |
Kgd | gcvH | BW34_02337 | BW34_02212 | Oxoglutarate dehydrogenase (Succinyl-transferring), E1 component. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.931 |
Kgd | gcvP | BW34_02337 | BW34_02213 | Oxoglutarate dehydrogenase (Succinyl-transferring), E1 component. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.988 |
Kgd | gcvT | BW34_02337 | BW34_02211 | Oxoglutarate dehydrogenase (Succinyl-transferring), E1 component. | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.831 |
Kgd | gltB | BW34_02337 | BW34_00397 | Oxoglutarate dehydrogenase (Succinyl-transferring), E1 component. | Glutamate synthase (NADPH/NADH) large chain. | 0.940 |
Kgd | glyA | BW34_02337 | BW34_02495 | Oxoglutarate dehydrogenase (Succinyl-transferring), E1 component. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.724 |
Kgd | lipA | BW34_02337 | BW34_00503 | Oxoglutarate dehydrogenase (Succinyl-transferring), E1 component. | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.514 |
Kgd | lipB | BW34_02337 | BW34_00502 | Oxoglutarate dehydrogenase (Succinyl-transferring), E1 component. | Octanoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.451 |
Kgd | lpdA | BW34_02337 | BW34_00046 | Oxoglutarate dehydrogenase (Succinyl-transferring), E1 component. | Dihydrolipoyl dehydrogenase. | 0.999 |
Kgd | lpdA-2 | BW34_02337 | BW34_00292 | Oxoglutarate dehydrogenase (Succinyl-transferring), E1 component. | Dihydrolipoyl dehydrogenase. | 0.999 |
LipM | Kgd | BW34_00813 | BW34_02337 | Lipoate-protein ligase A. | Oxoglutarate dehydrogenase (Succinyl-transferring), E1 component. | 0.899 |
LipM | gcvH | BW34_00813 | BW34_02212 | Lipoate-protein ligase A. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.943 |
LipM | gcvP | BW34_00813 | BW34_02213 | Lipoate-protein ligase A. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.430 |
LipM | lipA | BW34_00813 | BW34_00503 | Lipoate-protein ligase A. | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.940 |
LipM | lipB | BW34_00813 | BW34_00502 | Lipoate-protein ligase A. | Octanoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.924 |
LipM | lpdA | BW34_00813 | BW34_00046 | Lipoate-protein ligase A. | Dihydrolipoyl dehydrogenase. | 0.636 |
LipM | lpdA-2 | BW34_00813 | BW34_00292 | Lipoate-protein ligase A. | Dihydrolipoyl dehydrogenase. | 0.630 |
gcvH | Kgd | BW34_02212 | BW34_02337 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Oxoglutarate dehydrogenase (Succinyl-transferring), E1 component. | 0.931 |
gcvH | LipM | BW34_02212 | BW34_00813 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Lipoate-protein ligase A. | 0.943 |
gcvH | gcvP | BW34_02212 | BW34_02213 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.999 |